Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile

Rheumatoid arthritis (RA) is a multifactorial autoimmune disease, which is characterized by inflammation of synovial joints leading to the destruction of cartilage and bone. Infiltrating mast cells can be foun...

Source: Arthritis Research and Therapy - June 13, 2016 Category: Rheumatology Authors: Daniël van der Velden, H. Maxime Lagraauw, Anouk Wezel, Pierre Launay, Johan Kuiper, Tom W. J. Huizinga, René E. M. Toes, Ilze Bot and Jeroen N. Stoop Source Type: research