UC regents appoint Dr. Owen Witte University Professor

Dr. Owen Witte, renowned scientist and esteemed member of UCLA’s faculty, has been appointed a University Professor by the University of California Board of Regents. This appointment is reserved for scholars of the highest international distinction, who are respected as teachers of exceptional ability and whose contributions elevate the entire UC system. The University Professor title was established by the regents so that the entire UC system can benefit from the talents of outstanding faculty. Witte joins the ranks of just 40 UC faculty, including several Nobel laureates, who have received this honor since 1960. “Dr. Witte has made a significant impact at UCLA through his scientific achievements and visionary leadership,” said UCLA Chancellor Gene Block. “As University Professor, Witte’s efforts to unite and energize collaborative biomedical research across the UC system will only build upon his legacy — and further strengthen the competitiveness of our research enterprise.”   Witte’s accomplishments include impactful scientific discoveries, advocacy for science education funding and exemplary leadership as founding director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. His ability to create strategic partnerships across disciplines enables groups of elite clinicians, scientists and engineers to pursue breakthrough research with the shared goal of improving human health. Those...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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CONCLUSIONS: This study demonstrated the increased risk of skin cancer in transplant patients during the first 7 years of follow-up and made the dermatologists aware about the need of a regular cutaneous follow up for this subset of patients. PMID: 30229636 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
Authors: Caposiena Caro RD, Coppola A, Didona D PMID: 30229635 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
Authors: Day D, Burgess CM, Kircik LH Abstract BACKGROUND: Melatonin is an endogenous hormone commonly associated with regulation of sleep. However, over the last two decades, research has elucidated a range of effects associated with the compound, including anti-inflammatory, both direct and indirect antioxidant activity, tissue regenerative benefits, and preservation of mitochondrial function. Melatonin's anti-inflammatory and antioxidant support, coupled with its mitochondrial support, make it an intriguing target for use to support skin health. Human skin and hair follicles express functional melatonin receptor...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Publication date: Available online 20 September 2018Source: Journal of Biomedical InformaticsAuthor(s): Alex Graudenzi, Davide Maspero, Marzia Di Filippo, Marco Gnugnolo, Claudio Isella, Giancarlo Mauri, Enzo Medico, Marco Antoniotti, Chiara DamaniAbstractEffective stratification of cancer patients on the basis of their molecular make-up is a key open challenge. Given the altered and heterogenous nature of cancer metabolism, we here propose to use the overall expression of central carbon metabolism as biomarker to characterize groups of patients with important characteristics, such as response to ad-hoc therapeutic strateg...
Source: Journal of Biomedical Informatics - Category: Information Technology Source Type: research
Publication date: Available online 21 September 2018Source: The Lancet HIVAuthor(s): Silvia Franceschi
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
Publication date: Available online 21 September 2018Source: The Lancet HIVAuthor(s): Nancy A Hessol, Hannah Whittemore, Eric Vittinghoff, Ling C Hsu, Danning Ma, Susan Scheer, Sandra K SchwarczSummaryBackgroundCancer survivors are at increased risk for subsequent primary cancers. People living with HIV are at increased risk for AIDS-defining and non-AIDS-defining cancers, but little is known about their risk of first versus second primary cancers. We identified first and second primary cancers that occurred in above population expected numbers among people diagnosed with HIV in San Francisco, and compared first and second ...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
Publication date: Available online 19 September 2018Source: Microbial PathogenesisAuthor(s): Govindan Rajivgandhi, Thillaichidambaram Muneeswaran, Muthuchamy Maruthupandy, Kandasamy Saravanan, Vilwanathan Ravikumar, Natesan ManoharanAbstractThe current study aimed to identify bioactive compound from marine endophytic actinomycetes isolated from Gulf of Mannar, southeast coast of India. Among the isolated actinomycetes, strain GRG 4 exhibited excellent ability to inhibit colistin resistant (CR) Pseudomonas aeruginosa and Klebsiella pneumonia, which emerging threat to the world. The strain was identified as Streptomyces coer...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsThis study has elucidated the genome-wide effects of several adaptogenic herbal extracts in brain cells culture. These data highlight the consistent activation of ASRSPs by adaptogens in T98G neuroglia cells. The extracts affected many genes playing key roles in modulation of adaptive homeostasis, indicating their ability to modify gene expression to prevent stress-induced and aging-related disorders. Overall, this study provides a comprehensive look at the molecular mechanisms by which adaptogens exerts stress-protective effects.Graphycal abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
ConclusionThis is the first study demonstrating efficacy of DLA and mechanistic differences of DLAe vs. AS, against NSCLC cells. Compared to AS, DLA possesses qualities of a novel therapeutic for patients with NSCLC.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Conclusions: Sepsis is associated with increased or decreased risks for a small group of cancers. Factors that may explain these associations include etiologic effects of bacterial infections, inflammation, or use of antibiotics. Other associations may reflect the presence of precursor conditions (e.g., cirrhosis, colorectal polyps) or patterns in ascertainment of cancer and screening. PMID: 29982318 [PubMed - as supplied by publisher]
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Tags: Clin Infect Dis Source Type: research
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