In vitro and in vivo evaluation of the mechanisms of citalopram-induced hepatotoxicity.

In conclusion, it is suggested that citalopram hepatotoxicity might be a result of oxidative hazard leading to mitochondrial/lysosomal toxic connection and disorders in biochemical markers which were supported by histomorphological studies.
PMID: 27271269 [PubMed - as supplied by publisher]

Source: Archives of Pharmacal Research - June 5, 2016 Category: Drugs & Pharmacology Authors: Ahmadian E, Eftekhari A, Fard JK, Babaei H, Nayebi AM, Mohammadnejad D, Eghbal MA Tags: Arch Pharm Res Source Type: research