Differential Diagnosis between Primary Endocervical and Endometrial Adenocarcinoma using Immunohistochemical Staining of Estrogen Receptor, Vimentin, Carcinoembryonic Antigen and p16.

CONCLUSION: Vim and p16 are the significant IHC markers and a two-marker panel of Vim/p16 is recommended for using in differentiating primary ECAs and EMAs; which a pattern of negative Vim and positive p16 expression favors diagnosis of ECAs while the converse pattern of positive Vim and negative p16 staining points to diagnosis of EMAs. PMID: 27266224 [PubMed - in process]
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - Category: Journals (General) Tags: J Med Assoc Thai Source Type: research