Overexpression of BAT3 Alleviates Prion Protein Fragment PrP106-126-Induced Neuronal Apoptosis.

CONCLUSIONS: Our present data showed a novel molecular mechanism of PrP106-126-induced apoptotic process regulation through the overexpression of BAT3, which may be important for the basic regulatory mechanism of neuron survival in prion diseases and associated neurodegenerative diseases in vivo. PMID: 24629137 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24629137?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - March 15, 2014 Category: Neuroscience Authors: Song ZQ, Yang LF, Wang YS, Zhu T, Zhou XM, Yin XM, Yao HQ, Zhao DM Tags: CNS Neurosci Ther Source Type: research

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