Effectiveness and content analysis of interventions to enhance medication adherence in hypertension: a systematic review and meta-analysis protocol

The objective of this systematic review is to evaluate the effectiveness of medication adherence interventions for hypertension. In addition, we aim to explore what barriers and facilitators in the interventions may have been targeted and how these might be related to the effect size on blood pressure (BP). Methods This review is a hypertension-specific update to the previous Cochrane Review by Nieuwlaat et al. (2014) on interventions to enhance medication adherence. A systematic literature search will be carried out, and two authors will independently screen titles and abstracts for their eligibility for inclusion and independently extract data from the selected studies and assess the methodological quality using the Cochrane Collaboration Risk of Bias Tool. A meta-analysis will be conducted, and additionally, theoretical factors in interventions will be identified using the Theoretical Domains Framework. Discussion This review will generate new information by quantitatively evaluating the effectiveness of adherence interventions for hypertension and potentially identify which theoretical domains are associated with more effective interventions and which domains have not been the subject of intervention development. Systematic review registration PROSPERO CRD42016033358
Source: Systematic Reviews - Category: Global & Universal Source Type: research

Related Links:

Three medical stories that we didn't cover, explained.Medscape
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news
Publication date: Available online 12 December 2019Source: Pharmacological ResearchAuthor(s): Karan Naresh Amin, Elango Bhakkiyalakshmi, Jayasuriya Ravichandran, D.V.L. Sarada, Ramkumar Kunka MohanramAbstractEndothelial dysfunction (ED) is a key event in the onset and progression of vascular complications associated with diabetes. Regulation of endothelial function and the underlying signaling mechanisms in the progression of diabetes-induced vascular complications have been well established. Recent studies indicate that increased oxidative stress is an important determinant of endothelial injury and patients with hyperten...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Conclusion: This study suggests that all ARB-AML CTs compared favorably to AML monotherapy regarding short-term treatment response in uncomplicated HTN patients of Asian origin. AZL-AML prompted the most favorable treatment response. Safety profiles among the ARB-AML CTs were largely comparable. Due to the limited study size and small number of trials (direct evidence), our findings should best be interpreted as an exploratory effort importance to inform future research direction. PMID: 31827918 [PubMed]
Source: International Journal of Hypertension - Category: Cardiology Tags: Int J Hypertens Source Type: research
Authors: Körösi B, Vecsey-Nagy M, Kolossváry M, Nemcsik-Bencze Z, Szilveszter B, László A, Batta D, Gonda X, Merkely B, Rihmer Z, Maurovich-Horvat P, Eörsi D, Torzsa P, Nemcsik J Abstract Affective temperaments represent a biologically stable core of emotional reactivity and have previously been associated with hypertension and arterial stiffening. The age, when hypertension is initiated, is influenced by different factors, but the role of personality traits in this regard is not clarified yet. Our aim was to study the association between affective temperaments and the age at ons...
Source: International Journal of Hypertension - Category: Cardiology Tags: Int J Hypertens Source Type: research
This study aimed to estimate MetS status and its associations with geography, economic development, birth weight, and parental education of Chinese children and adolescents. METHODS: Data were derived from 15,045 participants aged 7-18 years across seven Chinese provinces. Physical measurement and blood tests were conducted to assess the five classical MetS components described by the International Diabetes Federation, including abdominal obesity (the essential component), high blood pressure, low high-density cholesterol (HDL-C), high triglyceride, and elevated fasting glucose (FG). Logistic regression was adopted to ...
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Source: Express Scripts _____ Express Scripts Launches First Digital Health Formulary for Apps &Devices (HIT Consultant): “Starting in January 2020, Express Scripts Digital Health Formulary will initially include 15 solutions for remote monitoring services and digital therapeutics that aid in the management of eight of the country’s most common chronic conditions: diabetes, prediabetes, hypertension, asthma, pulmonary disease, depression, anxiety, and insomnia … Participating health plans and employers can increase patients’ access to emerging products and technologies simply and affordably and...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology anxiety cognitive-behavioral-therapy depression digital health Digital Health Formulary digital therapeutics Express Scripts insomnia Learn to Live SilverCloud Source Type: blogs
Authors: Igboanugo S, Chen A, Mielke JG Abstract Birth asphyxia (BA) affects millions of newborns annually, especially in low-resource communities. Given that much of the attention to this point has focussed upon secondary prevention, we sought to inform the development of primary prevention strategies for BA in resource-limited settings by identifying maternal risk factors. To this end, we systematically reviewed the MEDLINE, PsychInfo, and EMBASE databases, and identified 38 relevant studies. Upon analysis, we found 12 maternal variables associated with BA, and thematically arranged them into 3 categories: sociod...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
HIGH blood pressure is strongly tied to unhealthy dietary decisions so following a nutritious diet is a surefire way to keep high blood pressure in check. A growing body of evidence is shedding a light on the best dietary items to lower high blood pressure, which includes a particular type of water.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusions: In Chinese elderly hypertensive patients, elevated resting heart rate was an independent predictor of ischemic stroke, and the optimal resting heart rate was around 70bpm. PMID: 31829063 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Right now, one in 12 children and adolescents in the US are severely obese. If that isn’t startling enough, consider this: among 12-to-15-year-olds, that number jumps to one in 10 — and among 16-to-19-year-olds, it is one in seven. According to the American Academy of Pediatrics (AAP), the best hope for many of these youths may be bariatric surgery. Bariatric surgery is surgery that helps with weight loss by making the stomach smaller and making other changes in the digestive system. It’s jarring to think about doing irreversible surgery on an adolescent — or a child, as the AAP discourages age limi...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health Children's Health Diabetes Diet and Weight Loss Parenting Source Type: blogs
More News: Cardiology | Cardiovascular | Heart | Hypertension | International Medicine & Public Health | Study