[Correspondence] Why use sex hormones in relapsing-remitting multiple sclerosis?

I read with interest Rhonda Voskuhl and colleagues' report1 of a phase 2 trial of the combination of estriol and glatiramer acetate for women with relapsing-remitting multiple sclerosis, and Annette Langer-Gould's Commentary2 on the Article. However, the authors did not seem to be aware of the immunomodulatory effect during pregnancy of interferon tau, which is produced by trophoblast cells in the human placenta.3 The structure and effects of this interferon are similar to those of interferon beta-1a (Rebif, Avonex) and interferon beta-1b (Betaseron, Biogen, Cambridge, MA, USA).

Source: Lancet Neurology - June 7, 2016 Category: Neurology Authors: Richard Lechtenberg Tags: Correspondence Source Type: research