New Data for KEYTRUDA® (pembrolizumab) in Combination with Talimogene Laherparepvec, Dabrafenib Plus Trametinib, or Low-Dose Ipilimumab in Advanced Melanoma Presented at 2016 ASCO Annual Meeting

Dateline City: KENILWORTH, N.J. KENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced findings from three separate studies evaluating the use of KEYTRUDA® (pembrolizumab), the company’s anti-PD-1 therapy, in combination with other treatment regimens including talimogene laherparepvec, dabrafenib plus trametinib, or low-dose ipilimumab in patients with advanced melanoma. Language: English Contact: MerckMedia Contacts:Pamela Eisele, 267-305-3558orAn Phan, 908-255-6325orInvestor Contacts:Teri Loxam, 908-740-1986orJustin Holko, 908-740-1879 Ticker Slug: Ticker: MRK Exchange: NYSE read more
Source: Merck.com - Research and Development News - Category: Pharmaceuticals Tags: Oncology Newsroom Research and Development News Corporate News Latest News #Merck #MRK $MRK ASCO Keytruda MSD Source Type: news

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SKIN cancer symptoms are triggered when skin cells start to divide uncontrollably. There are two main types of skin cancer, called melanoma and non-melanoma skin cancer. Watch out for this major warning sign of skin cancer.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
SKIN cancer symptoms are triggered when skin cells start to divide uncontrollably. There are two main types of skin cancer, called melanoma and non-melanoma skin cancer. Watch out for this major warning sign of skin cancer.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
SKIN cancer symptoms are triggered when skin cells start to divide uncontrollably. There are two main types of skin cancer, called melanoma and non-melanoma skin cancer. Watch out for this major warning sign of skin cancer.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Li J, Yan S, Wu N PMID: 30023129 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Metastatic melanoma represents a challenging clinical situation and, until relatively recently, there was an absence of effective treatment options. However, in 2011, the advanced melanoma treatment landscape ...
Source: Journal of Translational Medicine - Category: Research Authors: Tags: Meeting report Source Type: research
In conclusion, this study makes clear that lncRNA THOR is up-regulated in retinoblastoma, and its over-expression significantly enhances the malignant phenotype transformation of retinoblastoma cells through up-regulating c-myc expression via enhancing its combination with TGF2BP1 protein. Overall, our study illustrates that lncRNA THOR/c-myc molecular cascade might be another potent target for retinoblastoma treatment.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
AbstractEfforts to prevent melanoma, especially for those at elevated risk for the disease, should ideally begin during childhood. However, there are few preventive interventions targeting children who are at higher risk for melanoma due to a family history of the disease. Further, there are no educational interventions that aim to help these at-risk children understand their risk for melanoma and the ways in which preventive behaviors, such as sun protection, can mitigate their risk. The current paper describes a multidisciplinary team ’s process for creating a developmentally appropriate educational intervention ab...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
Condition:   Intervention:   Drug: omaveloxolone Sponsor:   Reata Pharmaceuticals, Inc. Available
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions“InterPreT Cancer Survival” is presented as an educational tool which engages the user through interactive features to improve the understanding of commonly reported cancer survival statistics. The tool has received positive feedback from a Cancer Research UK patient sounding board and there are further plans to incorporate more disease characteristics, e.g. stage.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
ConclusionsWe found some evidence that higher intake of folate from food only was associated with a modest increased risk of cutaneous melanoma. However, since other factors related to dietary folate intake may account for the observed association, our findings warrant further investigation.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
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