Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer
Conclusions
Batf-dependent IL-23R+IL-6+CD4+ Th17 cells critically control IL-23 driven colitis-associated tumour formation and the progression of sporadic colon tumours. Batf-dependent IL-23R+ T cells represent a potential future therapeutic target limiting CRC progression.
Source: Gut - Category: Gastroenterology Authors: Punkenburg, E., Vogler, T., Büttner, M., Amann, K., Waldner, M., Atreya, R., Abendroth, B., Mudter, J., Merkel, S., Gallmeier, E., Rose-John, S., Neurath, M. F., Hildner, K. Tags: Crohn's disease, Colon cancer Source Type: research
More News: Cancer | Cancer & Oncology | Colon Cancer | Colorectal Cancer | Crohn's Disease | Gastroenterology | Inflammatory Bowel Disease | Study