Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype

Notochordal cell conditioned medium (NCCM) derived from non-chondrodystrophic dogs has pro-anabolic and anti-catabolic effects upon nucleus pulposus (NP) cells. Here, for the first time, we assessed the abilit...

Source: Arthritis Research and Therapy - June 2, 2016 Category: Rheumatology Authors: Sebastian Müller, Lina Acevedo, Xiaomei Wang, M. Zia Karim, Ajay Matta, Arne Mehrkens, Stefan Schaeren, Sandra Feliciano, Marcel Jakob, Ivan Martin, Andrea Barbero and W. Mark Erwin Source Type: research