A possible heterozygous advantage in muscular dystrophy.

A possible heterozygous advantage in muscular dystrophy. S Afr Med J. 2016;106(6):10998 Authors: Emery AE Abstract In certain autosomal recessive disorders there is suggestive evidence that heterozygous carriers may have some selective advantage over normal homozygotes. These include, for example, cystic fibrosis, Tay-Sachs disease and phenylketonuria. The best example so far, however, is that of significant heterozygous advantage in sickle-cell anaemia with increased resistance to falciparum malaria. PMID: 27245530 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research