A possible heterozygous advantage in muscular dystrophy.
A possible heterozygous advantage in muscular dystrophy.
S Afr Med J. 2016;106(6):10998
Authors: Emery AE
Abstract
In certain autosomal recessive disorders there is suggestive evidence that heterozygous carriers may have some selective advantage over normal homozygotes. These include, for example, cystic fibrosis, Tay-Sachs disease and phenylketonuria. The best example so far, however, is that of significant heterozygous advantage in sickle-cell anaemia with increased resistance to falciparum malaria.
PMID: 27245530 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
More News: African Health | Anemia | Cystic Fibrosis | Malaria | Muscular Dystrophy | Phenylketonuria | Reflex Sympathetic Dystrophy | Sickle Cell Anemia