Correlation between apparent diffusion coefficients (ADC) on diffusion-weighted MRI and standardized uptake value (SUV) on FDG-PET/CT in patients with cancer: a meta-analysis

Conclusions Although both SUV and ADC are helpful parameters in oncology, the overall correlation between them is relatively poor regardless of tumor type. Different tumor types exhibited varied degree of correlation. The true correlation needs further validation by trials with a large sample of different tumor types. This study was supported by National Natural Science Foundation of China (Grant No. 81471692). Table 1. Subgroup analyses for the correlation between SUV and ADC.factorssubgroupnr (95% CI)p valuestudy designprospective22-0.34 (-0.39, -0.28)>0.05retrospective21-0.33 (-0.37, -0.29)scanning modalityPET/CT+MRI32-0.32 (-0.37, -0.28)>0.05PET/MRI11-0.33 (-0.37, -0.29)cancer typelung cancer11-0.42 (-0.48, -0.35)head-neck cancer6-0.29 (-0.41, -0.17)cervical cancer4-0.08 (-0.26, -0.10)breast cancer4-0.23 (-0.33, -0.13)
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: MTA II: Data Analysis & amp; Management Posters Source Type: research