A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride.

A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride.
Comb Chem High Throughput Screen. 2014 Mar 13;
Authors: Zolali A, Nasiri F, Omid-Niakan S
Abstract
An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without need to use of any catalyst.
PMID: 24628280 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - March 13, 2014 Category: Chemistry Authors: Zolali A, Nasiri F, Omid-Niakan S Tags: Comb Chem High Throughput Screen Source Type: research