Novel metabolites from the roots of Cadaba natalensis

Publication date: June 2016 Source:Phytochemistry Letters, Volume 16 Author(s): J.A. Monjane, A. Uamusse, O. Sterner From an extract of the roots of Cadaba natalensis Sond. the novel macrocyclic dibenzo-diazacyclododecanedione 1 was isolated together with (S)-2-ethyl-2-methyloxazolidin-5-one (2a). In addition, the five known compounds were obtained. Of these, (R)-5-ethyl-5-methyloxazolidin-2-one (3) is reported as a natural product for the first time. The structures of the isolated compounds were elucidated by analysis of the spectral data, 1D NMR (1H, 13C, and DEPT), 2D NMR (COSY, HMQC, HMBC, and NOESY), and HRESIMS, as well as by the comparison with previously reported data. Graphical abstract

Source: Phytochemistry Letters - May 28, 2016 Category: Chemistry Source Type: research