Underestimated burden: Epilepsy, multiple sclerosis, Parkinson’s impair sexuality
Neurological disorders can impair sexuality on a much more massive scale than frequently assumed, leaving loss of desire, erection problems and infertility in their wake. Both men and women are affected. A person’s self-esteem, love life and relationship with a significant other can all suffer.
Epileptic seizures often follow a circadian rhythm, which may eventually help guide therapy, researchers say.Medscape Medical News
Publication date: Available online 17 September 2018Source: European Journal of RadiologyAuthor(s): Salem Hannoun, Gabriel Kocevar, Françoise Durand-Dubief, Claudio Stamile, Amal Naji, Francois Cotton, Michele Cavallari, Charles R.G. Guttmann, Dominique Sappey-MarinierAbstractBackground and aimCerebellar peduncles (CP) can be probed by diffusion tensor imaging (DTI) to evaluate the integrity of cerebellar afferent and efferent networks. Damage to the CP in multiple sclerosis (MS) could lead to serious cognitive and mobility impairment. The aim of this study was to investigate the extent and the clinical impact of CP...
Blocking messages in lymphatic vessels from the brain to the immune system shows promise as a potential way to treat multiple sclerosis, according to a study.
Psoriasis is a relatively common immune-mediated chronic inflammatory skin disease. It is well known that interferon-beta, a drug used in the management of relapsing-remitting multiple sclerosis, could exacerbate or induce de novo psoriasis. There is limited evidence in the literature based only on case reports that natalizumab could induce or aggravate psoriasis. In this case study, we present a 33-year-old patient who developed plaque psoriasis during natalizumab treatment.Case Rep Neurol 2018;10:286 –291
ConclusionsOur data suggest that the hippocampal subfields are connected in distinct ways in different types of epilepsy. These results may provide important information that could help inform seizure focus hypothesis and in the surgical treatment of MRI-negative patients. These observations suggest that high-resolution dMRI-based tractography of the hippocampal subfields can detect subtle abnormalities in otherwise normal-appearing MRI-negative patients.
ConclusionsBesides older age at epilepsy onset and autoimmune comorbidity, seropositive patients cannot be distinguished from seronegative patients on the basis of clinical, EEG or neuroimaging data.
Condition: Drug Resistant Epilepsy Intervention: Drug: Cannabidiol Sponsor: John Available
Condition: Refractory Epilepsy Intervention: Biological: ADRC transplantation in autoimmune refractory epilepsy Sponsors: Mossakowski Medical Research Centre Polish Academy of Sciences; Institution of Mother and Child, Warsaw, Poland Active, not recruiting
Condition: Childhood or Juvenile Absence Epilepsy Intervention: Procedure: Timed repetitive sensory stimulation Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Recruiting
New research suggests that the brain sends a 'rogue' signal to the immune system through lymphatic vessels, thus triggering multiple sclerosis mechanisms.