Detection of erythroblast antibodies in mitogen-stimulated bone marrow cultures from patients with myelodysplastic syndromes.

CONCLUSION: MDS patients with anti-erythroblast autoimmunity showed increased BM apoptosis, suggesting that the autoimmune reaction may contribute to an unfavorable BM microenvironment for optimal erythropoiesis. PMID: 27232106 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27232106?dopt=Abstract

Source: Transfusion - May 26, 2016 Category: Hematology Authors: Zaninoni A, Imperiali FG, Cattaneo A, Soverini G, Binda F, Porretti L, Cortelezzi A, Barcellini W Tags: Transfusion Source Type: research