Why Not Pot? A Review of the Brain-based Risks of Cannabis
Conclusion Evaluating the potential harms of a commonly used drug—especially a complex substance like marijuana—is a challenging but vital task. Fully informed awareness of both the potential and proven benefits and the potential and proven harms of marijuana are necessary in order to have rational discussions with patients, teens, and decision makers regarding marijuana use. Based on a review of the current literature, we suggest the mnemonic DDUMB (dependence, driving, underachievement, mental illness, and “bad to worse”) as a tool that captures several of the more well-supported, brain-based risks associated with marijuana. Using this mnemonic, we reviewed five research-supported harms related to marijuana use. First, cannabis dependence (addiction) is real. Second, driving while under the influence of marijuana is unsafe. Third, marijuana use has a strong association with global underachievement. Fourth, marijuana elevates the risk of developing a psychotic illness and worsens the course of several serious mental health conditions in certain individuals. Fifth, though proving causality is complex, evidence supports a “bad to worse” or “gateway” role of cannabis in the development of other substance use disorders. Important to note, most of these harms are more likely to be present when marijuana use is frequent and starts early (i.e., in adolescence). Though we don’t always heed George Santayana’s aphorism about ...
In conclusion, the components of BGH may exert synergistic effects on improving gastric emptying via various targets. BGH is considered to be potentially useful for treating gastrointestinal dysmotility with psychological symptoms. PMID: 32089720 [PubMed]
Conclusion: The combination of JW-SZRD with lorazepam can significantly improve sleep quality with fewer AEs. It is an effective treatment and superior to lorazepam alone for chronic insomnia. PMID: 32089719 [PubMed]
AbstractOn 14 June 2017 at 00:54 h, the worst residential fire since the conclusion of the Second World War broke out in Flat 16, 4th floor of the 24-storey residential Grenfell Tower Block of flats, North Kensington, West London, UK. Seventy-one adults and children died, including one stillbirth. All victims of the Grenfell Towe r disaster who died at the scene underwent post-mortem computed tomography (PMCT) imaging using a mortuary-sited mobile computed tomography scanner. For the first time, to the authors’ knowledge, the disaster victim identification (DVI) radiology reporting was undertaken remote to the ...
In the past few years, Apple has greatly increased its presence in healthcare. The Cupertino, CA-based company has received FDA nods for apps associated with its technology and has found itself in several clinical trials. Most recently, the tech giant is seeing some movement in its partnership with Johnson &Johnsonâs Janssen Pharmaceutical unit. The companies just opened enrollment for the Heartline Study, which is designed to explore if the Heartline Study app on iPhone and heart health features on Apple Watch can improve health outcomes, including reducing the risk of stroke, with earlier detection ...
This study examines the challenges of providing access to pain management for people who have been socially or economically marginalized.Pain
[Observer] Two individuals, Joseph Kintu and Sulaiman Balinya, have sued Marie Stopes Uganda for negligence after they used defective Lifeguard condoms that burst during sex, leading to the contraction of HIV/Aids.
CD4:CD8 ratio is often compromised among older patients with HIV. Can recovery of this ratio be realized with antiretroviral therapy?HIV Medicine
(Reg Anesth Pain Med. 2019;44:578–585)
(Int J Obst Anesth. 2019;38:32–36)
(Acta Anaesthesiol Scand. 2018;62(1):134–137)
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