Influenza vaccination and egg allergy: another step forward

Commentary on: Turner PJ, Southern J, Andrews NJ, et al.. Safety of live attenuated influenza vaccine in young people with egg allergy: multicentre prospective cohort study. BJOG 2015;351:h6291. Context The occurrence of epidemics, like H1N1 in 2009, mobilises the scientific community to focus on resolution of problems. For many years, flu vaccination was a dilemma for physicians taking care of patients with an egg allergy. The small amount of egg found in the vaccine was considered a contraindication to immunisation. However, most people with this allergy are young and asthmatic, thus clearly the ones who could greatly benefit from this immunisation. While fractioned administration of intramuscular trivalent inactivated influenza vaccine (TIV) was previously deemed safe in egg allergic patients,1 a first publication in 2010 demonstrated the absence of anaphylactic reaction after H1N1 immunisation given in a single dose in a large cohort of people allergic...
Source: Evidence-Based Medicine - Category: Internal Medicine Authors: Tags: Epidemiologic studies, Vaccination programs, Immunology (including allergy), Influenza, Vaccination / immunisation, Asthma, Dermatology Aetiology/Harm Source Type: research