Medical News Today: Do young, female cancer survivors get enough info about infertility?

Currently, very few young, female cancer survivors opt for fertility preservation either before or after treatment. New research asks whether there is an information gap.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

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Conclusion: The DPP is the new source of non-toxic anti-cancer agents to use as a dietary supplement in the pre-treatment of cancer. PMID: 30397583 [PubMed]
Source: BioImpacts - Category: Research Tags: Bioimpacts Source Type: research
myLAB Box, a healthcare company based in California, has developed and pioneered an at-home sexually transmitted disease (STD) testing service. With the number of STDs rising, the Centers for Disease Control and Prevention estimates that nearly 20 mi...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Medicine Public Health Reproductive Medicine Source Type: blogs
Publication date: 6 November 2018Source: Cell Reports, Volume 25, Issue 6Author(s): Brian P. Hermann, Keren Cheng, Anukriti Singh, Lorena Roa-De La Cruz, Kazadi N. Mutoji, I-Chung Chen, Heidi Gildersleeve, Jake D. Lehle, Max Mayo, Birgit Westernströer, Nathan C. Law, Melissa J. Oatley, Ellen K. Velte, Bryan A. Niedenberger, Danielle Fritze, Sherman Silber, Christopher B. Geyer, Jon M. Oatley, John R. McCarreySummarySpermatogenesis is a complex and dynamic cellular differentiation process critical to male reproduction and sustained by spermatogonial stem cells (SSCs). Although patterns of gene expression have been...
Source: Cell Reports - Category: Cytology Source Type: research
We report a case of a 10-month-old boy with an incarcerated inguinal hernia who was discovered to have transverse testicular ectopia following hernia reduction. The patient was treated with herniorrhaphy and open transseptal orchiopexy.
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research
Publication date: Available online 3 November 2018Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Marc Kanbar, Francesca di Michele, Christine WynsAbstractTransplantation of own cryostored spermatogonial stem cells (SSCs) is a promising technique for fertility restoration when the SSC pool has been depleted.In this regard, cryopreservation of pre-pubertal testicular tissue or SSCs suspensions before gonadotoxic therapies is ethically accepted and increasingly proposed.SSC transplantation has also been considered to treat other causes of infertility relying on the possibility of propagat...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 1 November 2018Source: Stem Cell ReportsAuthor(s): Kaoru Miyazaki, Matthew T. Dyson, John S. Coon V, Yuichi Furukawa, Bahar D. Yilmaz, Tetsuo Maruyama, Serdar E. BulunSummaryDefective endometrial stromal fibroblasts (EMSFs) contribute to uterine factor infertility, endometriosis, and endometrial cancer. Induced pluripotent stem cells (iPSCs) derived from skin or bone marrow biopsies provide a patient-specific source that can be differentiated to various cells types. Replacement of abnormal EMSFs is a potential novel therapeutic approach for endometrial disease; however, the methodology or...
Source: Stem Cell Reports - Category: Stem Cells Source Type: research
Authors: Cui W, Stern C, Hickey M, Goldblatt F, Anazodo A, Stevenson WS, Phillips KA Abstract Alkylating chemotherapy is often used to treat pre-menopausal women for various malignancies and autoimmune diseases. Chemotherapy-associated ovarian failure is a potential consequence of this treatment which can cause infertility, and increases the risk of other long term adverse health sequelae. Randomised trials, predominantly of women undergoing alkylating chemotherapy for breast cancer, have shown evidence for the efficacy of gonadotropin-releasing hormone agonists (GnRHa) in preventing chemotherapy-associated ovarian...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
(Northwestern University) Researchers at Northwestern Medicine have taken the first step in bioengineering the human uterus to treat endometriosis, uterine-factor infertility and endometrial cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
From a historical perspective, the main clinical and research focuses have been on the long-term health outcomes of infertile women, including the effects of ovarian stimulation on the risk of mortality and cancer. However, in recent years, it has become more evident that a man's reproductive and somatic health also are closely related.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
AbstractWomen with a germline pathogenic variant in the BReast CAncer susceptibility genes (BRCA1 orBRCA2) have an increased risk of early-onset breast and ovarian cancer. In addition to weighing cancer screening and risk-reduction options, healthy BRCA mutation carriers of childbearing age may choose to preclude passing the mutation to the next generation. In the current study, we report on preimplantation genetic diagnosis (PGD) practices in BRCA-positive Israeli women who were offered PGD at no cost. Methods: we measured PGD uptake, decision satisfaction or regret, and predictors of uptake. Of the 70 participant female ...
Source: Journal of Genetic Counseling - Category: Genetics & Stem Cells Source Type: research
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