Single-Dose Drug Decreases Bone Loss in Newly Treated HIVSingle-Dose Drug Decreases Bone Loss in Newly Treated HIV

A single dose of zoledronic acid given at the start of ART decreases bone loss over the course of 48 weeks in HIV, according to a small, single-center, proof-of-concept study. Medscape Medical News
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

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Abstract Current challenges to antiretroviral therapy have opened new vistas in the search for novel drugs from natural products. This review focusses on plants as sources of inhibitors for human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Based on a systematic search of the literature, anti-HIV-1 reverse transcriptase activity was recorded for 132 plant species in 100 genera and 51 families. Seven families comprise 52.6% of plant species with anti-reverse transcriptase activity: Lamiaceae (13.7%), Fabaceae (10.7%), Euphorbiaceae (9.9%), Clusiaceae (6.1%), Asteraceae (4.6%), Combretaceae (4.6%), and Morace...
Source: Revista Brasileira de Farmacognosia - Category: Drugs & Pharmacology Source Type: research
A 25 year-old tuberculosis patient is treated at her home in Funafuti, the main island of Tuvalu in the South Pacific. Credit: UNDP Tuvalu/Aurélia Rusek.By External SourceUNITED NATIONS, Oct 17 2019 (IPS) A staggering 1.5 million people died from tuberculosis (TB) last year, the UN health agency said on Thursday, in an appeal for far greater funding and political support to eradicate the curable and preventable disease. Caused by the bacteria Mycobacterium tuberculosis, TB commonly causes persistent coughing, fatigue and weight loss. According to the World Health Organization (WHO) and its latest Global TB Report, a...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Poverty & SDGs Source Type: news
eSuction Distal Cap Aids Foreign Body Removal, Including Food Bolus Impactions CENTER VALLEY, Pa., Oct. 17, 2019 -- (Healthcare Sales &Marketing Network) -- Olympus, a global technology leader in designing and delivering innovative solutions for medic... Devices, Gastroenterology, Distribution Olympus, EndoTherapeutics, eSuction, endoscope
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Had a short visit, via a circuitous A14 diversion to Grafham Water reservoir while the sun was shining, drove home in the rain. Intriguingly, there was a warning sign about not swimming and needed higher-spec buoyancy aids because the water is aerated and so, presumably, of lower, less buoyant density than normal water. Anyway, a few photos. Not of the sign. Control Tower at Grafham Water Starling in a tree Waders Boat anglers Birdlife ticked on the morning; Tufted Duck, Great Black-backed Gull, Greylag Goose, Mandarin, Shelduck, Linnet, Robin, Wren, Starling, Stonechat, Meadow Pippet, Yellowhammer, Redwing, Goldfinch, Bla...
Source: David Bradley Sciencebase - Songs, Snaps, Science - Category: Science Authors: Tags: Sciencebase Source Type: blogs
Mind-reading exoskeletons, digital tattoos, 3D printed drugs, RFID implants for recreational purposes: mindblowing innovations come to medicine and healthcare almost every single day. We shortlisted some of the greatest ideas and developments that could give us a glimpse into the future of medicine, but we found so many that we had trouble fitting them into one article. Here are the first ten spectacular medical innovations to watch for. 1) Mixed reality opens new ways for medical education Augmented, virtual, and mixed reality are all technologies opening new worlds for the human senses. While the difference between...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine 3d printing artificial food brain-computer interface cyborg digital tattoos drug development exoskeleton gamification google glass health insurance Healthcare Innovation List Medical education medical techn Source Type: blogs
Publication date: December 2019Source: Microbial Pathogenesis, Volume 137Author(s): Faruq Abdulla, Utpal Kumar Adhikari, M. Kamal UddinAbstractTill now, AIDS, caused by the human immunodeficiency virus (HIV) is still a severe health problem worldwide. It weakens the immune system by targeting the T-helper cells. Specifically, the severity of the pandemic HIV-1 makes the emergence of an enduring effective vaccine against HIV-1. Therefore, we have applied a series of immunoinformatics approaches to the four conserved domains of HIV-1 integrase (IN) proteins to design an effective multi-epitope based subunit vaccine which mig...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This study searched for HTLV-1/2 antibodies in plasma samples of 625 HIV/AIDS patients from the municipality of Tubarao (Southern Santa Catarina), and disclosed 1.1% of positivity (0.48% HTLV-1, 0.48% HTLV-2 and 0.16% untypeable HTLV), and a positive correlation with the male sex (OR 4.16) and intravenous drug use (OR 35.18). Although the percentage of 1.1% appears to be low, it is 27.5 times higher than the percentage detected in blood donors. Since HTLV-1 and HTLV-2 are circulating in HIV-infected individuals in Southern Santa Catarina, and these retroviruses could cause a differently impact on the HIV/AIDS outcomes, the...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
CONCLUSIONS: The great diversity of motives illustrates the importance of offering a choice of PrEP-regimens. In counselling of MSM starting PrEP, choices for PrEP-regimens may be addressed as a continuum of flexible and changeable options over time. This may help individuals choose the PrEP-regimen that best fits their current sexual context, priorities and personal capabilities and therefore will be more easily adhered to. PMID: 31612621 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Source: Therapeutics and Clinical Risk Management - Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research
Authors: Snopkova S, Matyskova M, Havlickova K, Jarkovsky J, Svoboda M, Zavrelova J, Svacinka R, Penka M, Husa P Abstract OBJECTIVES: HIV-infected individuals are at higher risk of non-AIDS diseases associated with procoagulant status. Microparticles are elevated in disorders associated with thrombosis (e.g., cardiovascular diseases). We investigated the association between microparticle levels in untreated and treated HIV-infected subjects, and determined the association with immune status, viral replication, and duration of antiretroviral therapy. PATIENTS AND METHODS: We included 144 HIV-infected subjects, i...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
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