What Are Complications of Cerumen?

Discussion Cerumen or ear wax is produced in the outer third of the external auditory canal. It contains exfoliated squamous epithelium along with waxy substances. It is controlled by autosomal alleles and has two main phenotypes – “wet” cerumen which is dominant and common in Caucasian and African populations, and “dry” cerumen which is recessive and found more often in Asian populations. Cerumen protects the external canal and has some antibacterial and antifungal properties including against strains of Staphylococcus aureus, Pseudomonas aeroginosis, and Candida albicans. Staphylococcus aureus and Pseudomonas aeroginosis are the most common causes of otitis externa. The external auditory canal is a self cleaning mechanism which is assisted by jaw movement. It helps to trap dirt and keep out water. When this self cleaning system fails, cerumen accumulation and potential impaction can occur. Cerumen impaction is defined as “…accumulation that causes symptoms and prevents the needed assessment of the ear canal/tympanic membrane or audiovestibular system or both.” Cerumen impaction is common in children,the elderly and also in developmentally disabled populations. Treatment is by use of cerumenolytics, aural irrigation or manual removal. “Cerumenolytics work by hydrating the desquamated sheets of keratinocytes and by inducing keratinolysis causing disintegration of the cerumen.” A Cochrane Collaboration review foun...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

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Conclusions: Key findings of this study involved function-related outcomes and self-efficacy. Implications for Practice: Because these outcomes are particularly meaningful for patients, the integration of ANtiPain to routine clinical practice may be substantial. A larger study will be based on these findings.
Source: Cancer Nursing - Category: Nursing Tags: Articles Source Type: research
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Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
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Source: Gerontology - Category: Geriatrics Source Type: research
Malakoplakia is a rare chronic granulomatous disease that may affect many organs, including the lung, brain, adrenal glands, pancreas, bone, and the genitourinary tract. The gastrointestinal tract is the most common site of involvement outside of the urinary tract. Herein, we present a case of a 65-year-old male who presented with abdominal pain and unintentional weight loss. Physical examination findings were unremarkable, but colonoscopy revealed an isolated large, flat, soft, and pale lesion in the transverse colon. Histopathological examination of the lesion showed expansion of the lamina propria due to numerous lympho...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
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Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
A 67-year-old man with liver and retroperitoneal metastases from a gastrointestinal stromal tumor arising in the jejunum had been administered oral sunitinib for 2 months. He presented to our department with right-sided lower abdominal pain. His general condition was good, with no high-grade fever, and the other vital signs were also stable. Contrast-enhanced computed tomography was promptly performed, and pneumatosis cystoides intestinalis (PCI) was detected in a wide area around the ileocecal lesion. There were no signs of acute abdomen requiring emergency surgery due to conditions such as intestinal perforation, ischemi...
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Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
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Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
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Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Clinical Research: Patient Outcomes Research Source Type: research
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