Protecting bone in long-term HIV positive patients receiving antiretrovirals.

Protecting bone in long-term HIV positive patients receiving antiretrovirals. Expert Rev Anti Infect Ther. 2016 May 18; Authors: McGinty T, Mallon P Abstract As the population of people living with HIV ages, the increase in non-AIDs morbidities is expected to increase in parallel. Maintaining bone health in those with HIV will be an important area of focus for the HIV clinician to prevent the morbidity and mortality associated with fragility fractures, the principal clinical sequela of low bone mineral density (BMD). Rates of fractures and prevalence of low bone mineral density, a risk factor for future fragility fractures, are already increased in the HIV positive population. This review examines the strategies to maintain bone health in those living with HIV from screening through to managing those with established low BMD or fracture, including the role for choice of or modification of antiretroviral therapy to maintain bone health, as well as discussing future perspectives which may help achieve the long term aim of minimising the impact of low BMD in those with HIV. PMID: 27189695 [PubMed - as supplied by publisher]
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research