Scolopendin 2 leads to cellular stress response in Candida albicans

In conclusion, treatment of C. albicans with scolopendin 2 induced the apoptotic response at sublethal doses, which in turn led to mitochondrial dysfunction, metacaspase activation, and cell death. The cationic antimicrobial peptide scolopendin 2 from the centipede is a potential antifungal peptide, triggering the apoptotic response.
Source: Apoptosis - Category: Molecular Biology Source Type: research