Weight Loss Does Not Improve Infertility Treatment OutcomesWeight Loss Does Not Improve Infertility Treatment Outcomes

Obese, infertile women who participated in a weight loss program before infertility treatment were no more likely to conceive and deliver a healthy infant than those who had prompt treatment. Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

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Conditions:   Overweight;   Obesity;   Infertility, Female Interventions:   Drug: Saxenda;   Other: Lifestyle modification;   Diagnostic Test: Metabolomics;   Diagnostic Test: miRNA Sponsors:   University Hospitals Coventry and Warwickshire NHS Trust;   Kingston University;   University of Warwick;   University of Birmingham Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
by Iyad H. Manaserh, Lakshmikanth Chikkamenahalli, Samyuktha Ravi, Prabhatchandra R. Dube, Joshua J. Park, Jennifer W. Hill Insulin resistance and obesity are associated with reduced gonadotropin-releasing hormone (GnRH) release and infertility. Mice that lack insulin receptors (IRs) throughout development in both neuronal and non-neuronal brain cells are known to exhibit subfertility due to hypogonadotropic hypogonadi sm. However, attempts to recapitulate this phenotype by targeting specific neurons have failed. To determine whether astrocytic insulin sensing plays a role in the regulation of fertility, we generated mice...
Source: PLoS Biology: Archived Table of Contents - Category: Biology Authors: Source Type: research
In this study, we include endocrine and reproductive features in a rat model for PCOS and the effects of PBM on ovarian activities. Forty-five adult female Wistar rats PCOS-induced by a single dose of the estradiol valerate (EV) were used in the study. After the EV injection for PCO induction, rats were divided into 9 groups (n = 5/group) named C30, C45 and C60 (Control group), S30, S45 and S60 (PCO group) and L30, L45 and L60 (PCO/Laser group). The rats were irradiated with laser 3 times/week. The results shown that EV PCO-induced rats had increased body mass, reduced ovary mass, and reduced GSI. The plasma levels of ...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Klinefelter syndrome (KS), in which subjects have additional copies of X chromosomes, is the most common male sex chromosome abnormality, with a prevalence of 1 in 660 and an incidence of about 1 in 500-700 newborns. Its sign and symptoms include infertility, generally low testosterone levels, and an increased prevalence of obesity and metabolic syndrome. Epicardial fat thickness (EFT) reflects visceral adiposity rather than general obesity.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
The absolute of cancer remained very low at just 2%, and breast cancer was the most common type Related items fromOnMedica Only a third of women with regular bloating would see their GP Also in the press Fertility treatment does not appear to raise serious cancer risk Millennials top obesity chart before reaching middle age Reclassifying cancers 'will improve treatment'
Source: OnMedica Latest News - Category: UK Health Source Type: news
Semin Reprod Med 2018; 36: 183-194 DOI: 10.1055/s-0038-1675778Concerns remain about the health of children conceived by infertility treatment. Studies to date have predominantly not identified substantial long-term health effects after accounting for plurality, which is reassuring given the increasing numbers of children conceived by infertility treatment worldwide. However, as technological advances in treatment arise, ongoing studies remain critical for monitoring health effects. To study whether the techniques used in infertility treatment cause health differences, however, remains challenging due to identification of a...
Source: Seminars in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Review Article Source Type: research
AbstractMany countries tightly ration access to publicly funded fertility treatments such as in vitro fertilisation (IVF). One basis for excluding people from access to IVF is their body mass index. In this paper, I consider a number of potential justifications for such a policy, based on claims about effectiveness and cost-efficiency, and reject these as unsupported by available evidence. I consider an alternative justification: that those whose subfertility results from avoidable behaviours for which they are responsible are less deserving of treatment. I ultimately stop short of endorsing or rejecting such a justificati...
Source: Health Care Analysis - Category: Health Management Source Type: research
Abstract INTRODUCTION: Granulin (GRN) is an adipokine with proinflammatory features and plays important role in glucose metabolism and insulin resistance pathogenesis. It has been reported that granulin precursors were localized in developing follicles in animal studies. The purpose of this study was to evaluate the association of granulin levels with anthropometric features, glucose metabolism and ovarian reserve. METHODS: A total of 109 infertile women were included in this cross-sectional, prospective study, who attended to a tertiary clinic. All participants were categorised into diminished ovarian reserv...
Source: Endokrynologia Polska - Category: Endocrinology Authors: Tags: Endokrynol Pol Source Type: research
Muffin tops, man boobs, and bagel bumps: These are among the varied and perverse ways that the hormonal distortions inflicted on unwitting humans who consume the seeds of grasses, i.e., grains, show themselves. In our modern world filled with thousands of processed foods, there are plenty of landmines for health. Gummy bears and gumdrops will rot teeth, for instance. Indulge in a handful of dried prunes and you’ll have to schedule a substantial portion of your day on the toilet due to bowel irritants. But only wheat and grains are associated with a wide swath of health problems that range from autoimmune disease to m...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates grain-free gynecomastia man boobs man breasts testosterone undoctored wheat belly Source Type: blogs
Because it has become such a frequent item in everyday meals, suggesting that something so commonplace must be fine, people often ask: Is wheat really that bad? Let’s therefore catalog the health conditions that are associated with wheat consumption. Health conditions we know with 100% certainty are caused by consumption of wheat and related grains: Celiac disease, dermatitis herpetiformis, cerebellar ataxia, “idiopathic” peripheral neuropathy, temporal lobe seizures, gluten encephalopathy, type 1 diabetes, rheumatoid arthritis, autoimmune hepatitis, autoimmune pancreatitis, tooth decay Health conditions ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates autoimmune diabetes gluten-free grain-free grains wheat wheat belly Source Type: blogs
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