Reduced penicillin susceptibility of group B Streptococcus: an assessment of emergence in Grampian, Scotland.

Reduced penicillin susceptibility of group B Streptococcus: an assessment of emergence in Grampian, Scotland. Br J Biomed Sci. 2016;73(1):25-7 Authors: Cooper K, Abbott F, Gould IM PMID: 27182673 [PubMed - in process]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

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Health research authorities in England and Wales have given ethical approval to a trial aimed at preventing the most common cause of life-threatening infections in babies.
Source: NHS Networks - Category: UK Health Source Type: news
CONCLUSION: Of infection-related stillbirth cases in a large U.S. cohort, E coli, GBS, and enterococcus species were the most common bacterial pathogens and CMV the most common viral pathogen. PMID: 31698392 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
A £2.8million study will compare the ECM test and 'bedside test' on women across the UK to see if they reduce rates of Strep B, complications of which can kill children like Archie Powell (pictured).
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusions Bacterial studies were performed more frequently than viral and other studies. Cerebrospinal fluid bacterial culture was nearly 5 times more likely to yield a contaminant than a pathogen. The frequency of viral infection was likely underestimated as only 20% were tested, mainly by culture, which is suboptimal. These data suggest diagnostic practices for the evaluation of suspected community-acquired CNS infections in children need to be modified to reflect current epidemiology and highlight the need for greater accessibility to polymerase chain reaction for viral diagnostics. Furthermore, NMDAR ab–media...
Source: Pediatric Emergency Care - Category: Emergency Medicine Tags: Original Articles Source Type: research
Abstract Streptococcus agalactiae (group B Streptococcus, GBS) is a major pathogen in humans and animals. Pili and biofilm may be important virulence factors in this bacterial species. Here, biofilm production and the distribution of pilus variants among 134 GBS isolates from human and animal sources were evaluated. Biofilm production was significantly enhanced in 1% glucose-supplemented medium (p 
Source: Biofouling - Category: Molecular Biology Authors: Tags: Biofouling Source Type: research
This article will review established screening techniques, intrapartum antibiotic prophylactic regimens, and management specifically of the penicillin-allergic pregnant woman who is colonized with GBS.
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: New Antibiotics and Antibiotic Prophylaxis in Obstetrics Source Type: research
Streptococcus agalactiae or group B Streptococcus (GBS) is the cause of early- and late-onset GBS disease in neonates and can present as septicemia, meningitis, and pneumonia. Our objective was to compare the performance of two FDA-approved nucleic acid amplification tests (NAATs), the Panther Fusion and BD MAX systems, for detection of GBS in vaginal-rectal screening specimens. A total of 510 vaginal-rectal prepartum specimens were tested simultaneously in both NAATs following broth enrichment. Assay agreement was calculated using kappa statistics. Overall agreement between assays was 99.0% (505/510; 95% confidence interv...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Bacteriology Source Type: research
In this study, using molecular and synthetic biology approaches, biochemistry, radiolabeling techniques, and NMR and MS analyses, we examined the role of GacB, encoded in the S. pyogenes GAC gene cluster, in the GAC biosynthesis pathway. We demonstrate that GacB is the first characterized α-d-GlcNAc-β-1,4-l-rhamnosyltransferase that synthesizes the committed step in the biosynthesis of the GAC virulence determinant. Importantly, the substitution of S. pyogenes gacB with the homologous gene from Streptococcus agalactiae (Group B Streptococcus), Streptococcus equi subsp. zooepidemicus (Group C Streptococcus), Stre...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Editors ' Picks Source Type: research
Publication date: Available online 12 October 2019Source: Microbial PathogenesisAuthor(s): Matthew J. Sullivan, Glen C. UlettAbstractGroup B streptococcus (GBS) causes pyelonephritis in adults but the mechanisms of infection by which GBS infects the kidneys in vivo are unknown. We investigated GBS infection of the kidneys in mice following experimental challenge via the hematogenous route (transient bacteremia model) or transurethral route (bladder infection and cystitis model). Adult female mice were examined for bacterial dissemination to the kidneys and other organ systems at 24–72 h and tissue samples were asse...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
We present the case of a patient who developed a fulminant case of GBS necrotizing fasciitis on a backdrop of a previously undiagnosed malignancy, and review the relevant literature.
Source: IDCases - Category: Infectious Diseases Source Type: research
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