Sequelae of patients treated for pulmonary tuberculosis in chest clinic, tikur anbessa specialized hospital (tash), addis ababa, ethiopia.

CONCLUSIONS: Fibrosis and bronchiectasis were the most common pulmonary complications of tuberculosis among patients encountered at the TASH chest clinic during the study period. This demonstrates the impact of pulmonary tuberculosis is beyond management of active disease. PMID: 27182582 [PubMed - in process]
Source: Ethiopian Medical Journal - Category: African Health Tags: Ethiop Med J Source Type: research

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Publication date: Available online 14 February 2020Source: Preventive Veterinary MedicineAuthor(s): Julio Isla, Mariana Boadella, Jose Antonio Ortiz, Christian GortázarAbstractMycobacterial diseases are important health issues in farmed deer. The single intradermal tuberculin test is the standard test for tuberculosis testing in deer. We studied two factors which might influence the response of deer to skin testing: the inoculation site and the injection device. Deer included in this study were 2.5 years old farmed red deer (Cervus elaphus) hinds (n = 80). Two areas of 3 cm ×&thinsp...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
ConclusionResistance to first-line TB drugs is higher in extra-pulmonary TB isolates than pulmonary isolates. Nearly one-fourth of all M. tuberculosis clinical strains were resistant to the antibiotics tested in mono-resistant or multi-resistant manners. Women had greater resistance to TB drug ethambutol as compared to men. Meanwhile, extra-pulmonary TB specimens, specifically that from tissue cultures, showed greater resistance to Isoniazid than other clinical specimens.
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
ConclusionTuberculous mastitis is extremely rare variant of extrapulmonary tuberculosis. However, it should be kept in the mind of physicians and pathologists while approaching a breast mass, especially in endemic area.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Publication date: Available online 14 February 2020Source: The Lancet Respiratory MedicineAuthor(s): Hridesh Mishra, Byron W P Reeve, Zaida Palmer, Judy Caldwell, Tania Dolby, Charissa C Naidoo, Jennifer G Jackson, Samuel G Schumacher, Claudia M Denkinger, Andreas H Diacon, Paul D van Helden, Florian M Marx, Robin M Warren, Grant TheronSummaryBackgroundXpert MTB/RIF Ultra (Ultra) is a new test for tuberculosis undergoing global roll-out. We assessed the performance of Ultra compared with Xpert MTB/RIF (Xpert) in an HIV-endemic setting where previous tuberculosis is frequent and current test performance is suboptimal.Method...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Authors: Banu EA, Nechita A, Elkan-Cojocaru EM, Baciu G, Manole A, Chelaru L Abstract Introduction: In the context of the global tuberculosis (TB) burden, children represent 10% of all cases, with high incidence rates still reported by many regions worldwide. The study aim was to determine whether there is a correlation between TB clinical diagnosis and low birth weight in children at various ages. Material and methods: The study was conducted between 2010 and 2014, on a group of 1783 pediatric patients and a subgroup of 137 pediatric patients with low birth weight (LBW). Data were collected from patients' reco...
Source: Archives of Medical Science - Category: Biomedical Science Tags: Arch Med Sci Source Type: research
Conclusions: The technique used was adequate to guide surveillance actions in the country and allows articulation between local surveillance efforts and other sectors to resolve health problems caused by infectious and parasitic diseases and associated factors. PMID: 32051684 [PubMed]
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
ConclusionTaken together, these results demonstrate that PAS resistance and mutations in thekatG gene, inhA promoter or oxyR–ahpC intergenic region in INH-resistant M. tuberculosis have little effect on pasiniazid susceptibility.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionThe study described key factors associated with TB and showed the different epidemiological characteristics between the three groups compared. The findings support the need for migrant-specific TB elimination action plans if TB elimination targets are to be achieved.
Source: Journal of Public Health - Category: Health Management Source Type: research
Authors: PMID: 32057258 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research
AbstractBacillus Calmette-Gu érin (BCG) has been in use for nearly 100  years and is the only licensed TB vaccine. While BCG provides protection against disseminated TB in infants, its protection against adult pulmonary tuberculosis (PTB) is variable. To achieve the ambitious goal of eradicating TB worldwide by 2050, there is an urgent need to develop novel TB vaccine s. Currently, there are more than a dozen novel TB vaccines including prophylactic and therapeutic at different stages of clinical research. This literature review provides an overview of the clinical status of candidate TB vaccines and discusses ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
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