Keep Busy! Stay Sharp!

Title: Keep Busy! Stay Sharp!Category: Health NewsCreated: 5/17/2016 12:00:00 AMLast Editorial Review: 5/18/2016 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news

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Scientists at Duke University in the US gave donepezil to rats who had been exposed to excessive quantities of alcohol over the course of 16 days.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Dysfunction of the blood-brain barrier, allowing molecules and cells not normally present in the central nervous system to enter, is one of the features of dementia. If nothing else, this causes inflammation in the brain as the immune system is roused to try to clear out the unwanted materials. Chronic inflammation in the immune cells of the central nervous system is an important part of the progression of neurodegenerative conditions, and in Alzheimer's disease shows up after the initial accumulation of amyloid-β. This sequence of events may be due in part to amyloid-β causing blood-brain barrier dysfunction, th...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Scientists from Wake Forest Baptist Health in North Carolina looked at 14 adults with mild cognitive impairment, which increases a person's risk of developing dementia.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ALZHEIMER ’S disease is the most common cause of dementia. The symptoms of the progressive disease can seem slight at first. A new study has provided a striking explanation for one early warning sign.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This study employed group independent component analysis (ICA) to analyze resting state fMRI data from 158 participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) with baseline diagnoses of normal cognition or early mild cognitive impairment (eMCI). pDMN and aDMN were defined on a subject-specific basis; prefrontal areas were selected from the Brodmann atlas (BA 6, 44, 8, and 9). Moderation regression analyses examined whether sex and amyloid PET positivity (A+/-) moderated effects of apolipoprotein Ɛ4 (APOE ε4) on connectivity between left PFC, aDMN, and pDMN; and between aDMN and pDMN. Significa...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Notice NOT-NS-20-001 from the NIH Guide for Grants and Contracts
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
In this study, Warmack produced crystals, both the normal and kinked types, in 15 of beta amyloid ’s amino acids. She used a modified type of cryo-electron microscopy to analyze the crystals. Cryo-electron microscopy, whose development won its creators the 2017 Nobel Prize in chemistry, enables scientists to see large biomolecules in extraordinary detail. Professor Tamir Gonen pioneered the mo dified microscopy, called microcrystal electron diffraction, which enables scientists to study biomolecules of any size.Eisenberg is UCLA ’s Paul D. Boyer Professor of Molecular Biology and a Howard Hughes Medical Institu...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
MONDAY, Aug. 19, 2019 -- Heat waves can pose a serious risk to people with Alzheimer's disease, so their families should know how to keep them safe, advocates say. Extreme heat is " dangerous for everyone, but especially for someone with Alzheimer's...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
Source: The Scientist - Category: Science Tags: Image of the Day Source Type: news
Maintaining fitness through the practice of regular exercise improves health in old age, slowing the pace of damage to the brain and consequent cognitive decline. While there is largely only correlational data in humans to show a link between exercise and a slower pace of neurodegeneration, many animal studies make it clear that exercise causes an improved trajectory for health in later life. It does not extend overall life span in mice, as is the case for calorie restriction, but is otherwise very effective for an intervention that is essentially free. This beneficial outcome is likely due to a combination of overl...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
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