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Penis transplant: welcome to the frontier of a fascinating science | Celine Gounder

Transplant medicine has overcome problems of infection, rejection and surgical complexity. Now we just need more people to become donorsThe first penile transplant in the US was performed on cancer survivor Thomas Manning at Harvard’s Massachusetts General Hospital last week. This paves the way for the treatment of other cancer patients, wounded veterans, burn victims and all those who’ve suffered genital trauma or needed radical surgery to save their lives. Transplanting a penis is technically much simpler than transplanting a lung or liver, so why did it take this long?Transplant medicine is much older than many realize. Over 3,000 years ago, the ancient Indian physician Sushruta used skin transplants – more commonly today called grafts – to reconstruct noses amputated as punishment for crimes. As early as the 1600s, patients were treated with animal blood infusions or bone transplants. But early transplant medicine was thwarted by infections and the immune system. Our skin is one of our most basic defenses – acting like the high walls and moat of a medieval city – guarding us against invasion by all sorts of microbes in the environment. An appreciation of the germ theory and the need for antisepsis – at first with carbolic acid, a corrosive chemical that burns, bleaches and numbs the skin and is poisonous to the lungs if inhaled – helped bring down surgical death rates dramatically. Anesthesia made it possible to undertake lo...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Science Society US news World news Medical research Source Type: news

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One month after stepping down as head of research and development at Gilead Sciences, Norbert Bischofberger has taken the helm of a new cancer drug startup in Cambridge. Kronos Bio formally announced its launch on Wednesday. The company is operating out of LabCentral, and has collected $18 million in seed financing from various venture funds and individual investors. They include Bischofberger, who spent more than 30 years with California-based Gilead (Nasdaq: GIL D) before leaving in April. Kronos’…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Norbert Bischofberger rides again. The 62-year-old former chief scientific officer at Gilead Sciences Inc. (NASDAQ: GILD), who stepped down last month after overseeing the development of groundbreaking and sometimes-controversial HIV and hepatitis C drugs, will become president and CEO of Cambridge, Mass., cancer-fighting startup K ronos Bio Inc. And Bischofberger, an investor in Kronos' $18 million seed round disclosed Wednesday, isn't alone: Also investing in the company is Gilead's executive…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Claire Wineland vowed she wouldn't have a lung transplant, but her decline from cystic fibrosis made her reconsider. Now she's fighting for a chance at survival.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Jie Wang, Gejing De, Qiaoxin Yue, Hai Ma, Jintang Cheng, Guangwei Zhu, Maobo Du, Hong Yi, Qinghe Zhao, Yanjun Chen
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Hua Xing, Lirong Zhang, Jinshu Ma, Zhen Liu, Changlong Song, Yuxia Liu
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
You are probably familiar with the Mediterranean diet, which emphasizes fruits, vegetables, nuts, whole grains and olive oil. The diet has been associated with a lower incidence of cardiovascular disease, cancer and Type 2 diabetes, as well as a reduced risk of Alzheimer's and Parkinson's diseases. But there's another diet that has its roots overseas, and it appears to offer similar health benefits.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Olympic athletes have a secret that most mere mortals just don't get. And it's the same secret that can make you a gold-medal superstar in bed.  I'm talking about oxygen.  Olympians understand that every cell in your body is designed to burn oxygen. Cut back on oxygen and all cellular processes slow down. You start to become tired or short of breath. So, high concentrations of oxygen in every cell in your body makes the difference between a gold medal and an "also ran."  It's the same for you in just about every part of your life. With plenty of oxygen, your body pulses with energy....
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
Conclusion Vaccine companies have regularly used blood and body parts from killed cows, dogs, worms, mice, chickens, human babies, monkeys, guinea pigs, rabbits, hamsters, rats, etc., to make these vaccines, so using foreskin from newborn babies may not surprise some. For many, it is appalling. [28] Circumcisions fuel multi-billion dollar industries. If you see neonatal foreskin for sale, which is very easy to find on the internet, remember that these newborn children didn’t consent to being circumcised and they didn’t consent for their foreskin to be sold, used for research purposes, or to be injected into the...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Augustina Ursino Top Stories circumcision truth about vaccines Source Type: blogs
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
BOSTON (CBS) – The man who received the nation’s first penis transplant at Mass General Hospital in Boston wants everyone to know how grateful he is. Tom Manning isn’t hiding. There are no taboos. Manning is eager to tell people about his experience in honest terms, sharing the story of this life-changing medical breakthrough that he had been hoping for years could become a reality. “When my surgeon operated on me, some of the first words out of my mouth were, ‘When am I going to get my transplant?’” Manning told WBZ-TV’s Lisa Hughes. “I just thought, if you can replace...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Lisa Hughes Mass General penis transplant Thomas Manning Source Type: news
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