Penis transplant: welcome to the frontier of a fascinating science | Celine Gounder

Transplant medicine has overcome problems of infection, rejection and surgical complexity. Now we just need more people to become donorsThe first penile transplant in the US was performed on cancer survivor Thomas Manning at Harvard’s Massachusetts General Hospital last week. This paves the way for the treatment of other cancer patients, wounded veterans, burn victims and all those who’ve suffered genital trauma or needed radical surgery to save their lives. Transplanting a penis is technically much simpler than transplanting a lung or liver, so why did it take this long?Transplant medicine is much older than many realize. Over 3,000 years ago, the ancient Indian physician Sushruta used skin transplants – more commonly today called grafts – to reconstruct noses amputated as punishment for crimes. As early as the 1600s, patients were treated with animal blood infusions or bone transplants. But early transplant medicine was thwarted by infections and the immune system. Our skin is one of our most basic defenses – acting like the high walls and moat of a medieval city – guarding us against invasion by all sorts of microbes in the environment. An appreciation of the germ theory and the need for antisepsis – at first with carbolic acid, a corrosive chemical that burns, bleaches and numbs the skin and is poisonous to the lungs if inhaled – helped bring down surgical death rates dramatically. Anesthesia made it possible to undertake lo...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Science Society US news World news Medical research Source Type: news

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This study aimed to determine the oral health knowledge (OHK) of Hispanic adults in Iowa to identify potential gaps in knowledge. METHODS: This cross-sectional study included a convenience sample of self-identifying Hispanic adults. Data pertaining to oral health literacy and demographic, cultural, and dental characteristics were collected. OHK was assessed with the Conceptual Measure of Oral Health Knowledge, and it was categorized as low or high. Bivariate analyses and multiple logistic regression models were conducted to identify the variables related to OHK (P
Source: Journal of the American Dental Association - Category: Dentistry Tags: J Am Dent Assoc Source Type: research
Certain fats found in seafood may help keep you healthy for years to come, according to a new study published in the BMJ. Higher blood levels of omega-3 polyunsaturated fatty acids — healthy fats found in foods such as fish, nuts, leafy greens and vegetable and flaxseed oils — were associated with a greater chance of healthy aging, according to the observational research. Omega-3s found in seafood seemed to have the strongest effect, says study co-author Heidi Lai, a postdoctoral fellow at Tufts’ Friedman School of Nutrition Science and Policy. “There had been studies that looked at the relationship...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition healthytime Source Type: news
Authors: Wani TH, Surendran S, Mishra VS, Chaturvedi J, Chowdhury G, Chakrabarty A Abstract Sepantronium bromide (YM155), originally developed against the anti-apoptotic protein survivin, performed exceptionally well in pre-clinical and phase I clinical trials. However, in phase II trials of several cancer types including breast cancer it performed poorly. Additionally, no definitive correlation between survivin level and response to therapy was found. In an attempt to understand the true reason of the late-stage failure of this promising drug, we developed YM155-resistant MCF-7 breast cancer cell line and characte...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Conclusion: ILND is burned by a high complication rate. VEIL provides a less invasive approach and a saphenous-sparing technique ensures a lower complication rate, reducing lymphorrhea, skin necrosis and wound complications (1 – 3). In experienced laparoscopic hands, VEIL is a safe and effective treatment.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusion: ILND is burned by a high complication rate. VEIL provides a less invasive approach and a saphenous-sparing technique ensures a lower complication rate, reducing lymphorrhea, skin necrosis and wound complications (1 – 3). In experienced laparoscopic hands, VEIL is a safe and effective treatment.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusion: ILND is burned by a high complication rate. VEIL provides a less invasive approach and a saphenous-sparing technique ensures a lower complication rate, reducing lymphorrhea, skin necrosis and wound complications (1 – 3). In experienced laparoscopic hands, VEIL is a safe and effective treatment.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Olympic athletes have a secret that most mere mortals just don't get. And it's the same secret that can make you a gold-medal superstar in bed.  I'm talking about oxygen.  Olympians understand that every cell in your body is designed to burn oxygen. Cut back on oxygen and all cellular processes slow down. You start to become tired or short of breath. So, high concentrations of oxygen in every cell in your body makes the difference between a gold medal and an "also ran."  It's the same for you in just about every part of your life. With plenty of oxygen, your body pulses with energy....
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
Conclusion Vaccine companies have regularly used blood and body parts from killed cows, dogs, worms, mice, chickens, human babies, monkeys, guinea pigs, rabbits, hamsters, rats, etc., to make these vaccines, so using foreskin from newborn babies may not surprise some. For many, it is appalling. [28] Circumcisions fuel multi-billion dollar industries. If you see neonatal foreskin for sale, which is very easy to find on the internet, remember that these newborn children didn’t consent to being circumcised and they didn’t consent for their foreskin to be sold, used for research purposes, or to be injected into the...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Augustina Ursino Top Stories circumcision truth about vaccines Source Type: blogs
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
BOSTON (CBS) – The man who received the nation’s first penis transplant at Mass General Hospital in Boston wants everyone to know how grateful he is. Tom Manning isn’t hiding. There are no taboos. Manning is eager to tell people about his experience in honest terms, sharing the story of this life-changing medical breakthrough that he had been hoping for years could become a reality. “When my surgeon operated on me, some of the first words out of my mouth were, ‘When am I going to get my transplant?’” Manning told WBZ-TV’s Lisa Hughes. “I just thought, if you can replace...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Lisa Hughes Mass General penis transplant Thomas Manning Source Type: news
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