Infertility risk posed by endometriosis may be half of previous estimation

The infertility risk posed by endometriosis is about half previous estimates and indicates a possible detection bias in earlier studies, according to a new report.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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The first case is a 36-years-old nulliparous patient was referred for dysmenorrhea, deep dyspareunia and infertility. Physical examination revealed a tender retrocervical nodule that was confirmed by transvaginal ultrasound with bowel preparation. Imaging also showed a 3 cm rectosigmoid nodule compromising the muscularis and the submucosa and an appendiceal nodule measuring 1.2  × 0.7 × 0.6 cm. Patient opted for expectant management of endometriosis, underwent in-vitro fertilization (IVF) treatment for infertility and had a successful pregnancy and delivery.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: IMAGES IN Gynecological Surgery Source Type: research
Abstract Endometriosis, a common gynecological disease, is associated with pelvic pain and infertility. Endometriosis affects approximately 10% of women, but that number increases to 30-50% in symptomatic premenopausal women. Despite the prevalence of endometriosis, the cause has yet to be fully elucidated. Recent study of the molecular pathways of endometrial cancer has brought the long non-coding RNA (lncRNA) H19 to our attention. In this paper, we explored the role of lncRNA-H19 in endometrial tissue proliferation. We found that ectopic endometrial cells taken from women with endometriosis showed elevated level...
Source: Experimental Cell Research - Category: Cytology Authors: Tags: Exp Cell Res Source Type: research
CONCLUSIONS: The omega-6/3 and omega-9/6 nutraceuticals decreased pain compared to the controls. There was no improvement in fertility in any of the tested groups. PMID: 31066787 [PubMed - in process]
Source: Acta Cirurgica Brasileira - Category: Surgery Authors: Tags: Acta Cir Bras Source Type: research
(Abstracted from J Minim Invasive Gynecol 2019;26:71–77) The primary sequelae of endometriosis are infertility and chronic pelvic pain (CPP). Nearly 40% of women with endometriosis are infertile, and 71% to 87% have CPP.
Source: Obstetrical and Gynecological Survey - Category: OBGYN Tags: GYNECOLOGY: OPERATIVE GYNECOLOGY Source Type: research
Xiao Wang and Haja N. Kadarmideen* Quantitative Genomics, Bioinformatics and Computational Biology Group, Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kongens Lyngby, Denmark Epigenetic changes are important for understanding complex trait variation and inheritance in pigs that are also a valuable biomedical model for human health research. Testis is the main organ for reproduction and boar taint in pigs; however, there have been no studies to-date on adult pig testis epigenome. The main objective of this study was to establish a genome-wide DNA methylation map of pig t...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Infertility is estimated to affect about 10% to 15% of couples. Most cases of infertility have etiologies that can be attributed to tubal factors, ovulatory dysfunction, endometriosis, uterine factor, male factor, or diminished ovarian reserve, while the remainder often do not have a known attributable cause, that is, unexplained infertility. The current manuscript summarizes the contemporary management of unexplained infertility.
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: An Update in REI and ART Source Type: research
ConclusionsOur findings show that Calligonum comosum targets multiple, fundamental processes in the pathogenesis of endometriosis, which may be beneficial for the treatment of this common gynecological disorder.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
One of 2 new first-of-kind studies on HPV and infertility suggests that high-risk HPV may ascend to infect the upper genital tract, causing endometriosis and affecting fertility.
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Women ' s Health Source Type: news
Authors: Bulun SE, Yilmaz BD, Sison C, Miyazaki K, Bernardi L, Liu S, Kohlmeier A, Yin P, Milad M, Wei J Abstract Pelvic endometriosis is a complex syndrome characterized by an estrogen-dependent chronic inflammatory process that affects primarily pelvic tissues, including the ovaries. It is caused when shed endometrial tissue travels retrograde into the lower abdominal cavity. Endometriosis is the most common cause of chronic pelvic pain in women and is associated with infertility. The underlying pathologic mechanisms in the intracavitary endometrium and extra-uterine endometriotic tissue involve defectively progr...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
In this study, vaginal microbiome was divided in five biotypes, being four of them dominated by lactobacilli and considered as healthy (pH 5.0) and higher diversity. In a healthy status, microbiota is balanced and forms a stable ecological unit dominated by Lactobacillus species, which fixes pH below 5.0 and controls non-desirable groups. In a pathogenic process, the microbiome shifts to a dysbiotic state, in which lactobacilli drop, pH is increased to values above 4.5 and other groups such as Gardnerella, Atopobium, Prevotella, and Streptococcus, among others, can overgrow (Srinivasan et al., 2012). Short chain fatty acid...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
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