Transplantation: Females hold the key to ischaemia tolerance

Nature Reviews Nephrology 12, 316 (2016). doi:10.1038/nrneph.2016.63 Author: Jessica K. Edwards Females have an increased capacity to recover from ischaemia–reperfusion injury (IRI) compared to males, according to new research. Female mice deficient in the estrogen receptor displayed exacerbated renal IRI, but mice that received supplemental estrogen were protected. This sex-specific difference was also implied from analysis
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research