Predictors of dysgeusia in patients with oropharyngeal cancer treated with chemo-IMRT
Dysgeusia is significant factor reducing quality of life and worsening dysphagia in patients receiving chemoradiotherapy for head and neck cancer. We investigated effects of doses to the oral cavity, salivary output (required to dissolve food particles) and patient-reported xerostomia, on patient-reported dysgeusia in a prospective study. Our main findings were significant effect of oral cavity doses ( D50=53 Gy at 3 months), and patient-reported xerostomia, but not salivary flow rates, on severity of dysgeusia.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Eli Sapir, Yebin Tao, Felix Feng, Stuart Samuels, Issam El Naqa, Carol A. Murdoch-Kinch, Mary Feng, Matthew Schipper, Avraham Eisbruch Tags: Clinical Investigation Source Type: research
More News: Biology | Cancer | Cancer & Oncology | Head and Neck Cancer | Intensity-Modulated Radiation Therapy | Oral Cancer | Oral Cavity Cancer | Oropharyngeal Cancer | Physics | Radiology | Study | Xerostomia