Could POLIO help cure cancer? Therapy harnessing the virus 'destroys brain tumors'

Experts at Duke University found a genetically modified version of the polio virus infects cancer cells, removing their protective shield, that hides them from the immune system, allowing the body to kill it off.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

Related Links:

An ancient scourge -- the polio virus -- may be an unexpected friend to people battling one of the deadliest brain cancers, new research shows.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Doctors using the polio virus to treat aggressive brain tumors called glioblastomas report promising results. Sen. John McCain has this type of cancer, and so did Sen. Ted Kennedy. Of 61 patients treated in one study, 21 percent were still alive at the three-year mark. That's compared with just four percent of patients who received standard cancer treatment. Dr. David Agus, director of USC Norris Westside Cancer Center, joins "CBS This Morning" to discuss the treatment. He also weighs in on a study that showed flight attendants had a higher cancer prevalence than the general population.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Survival was better than expected for patients in a small study at Duke University who were given genetically modified poliovirus, which helped their bodies attack the cancer, doctors report.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
The idea that viruses may be co-opted to do good rather than harm isn’t entirely new; researchers have been attempting to harness the power of viruses and bacteria for more than a century. Vaccines are the shining example of using bad bugs to do good in priming the immune system to fight disease. But disease-causing viruses aren’t always easy to corral, and attempts to use them to activate the immune system against things other than fellow bacteria and viruses — including cancer, for example — have not been so successful. There is only one approved virus-based treatment for cancer, which uses herpes...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Cancer healthytime Source Type: news
TUESDAY, June 26, 2018 -- An ancient scourge -- the polio virus -- may be an unexpected friend to people battling one of the deadliest brain cancers, new research shows. The new therapy uses a tweaked, harmless form of the polio virus to...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
(Solving Kids' Cancer) A Phase 1 clinical trial leveraging the re-engineered polio virus is now open for enrollment to children 12 years and older at the Preston Robert Tisch Brain Tumor Center, Duke University Medical Center. After years of following the progress of this promising therapy against adult glioblastoma and working with the research team on behalf of children, Solving Kids' Cancer teamed up with The Andrew McDonough B+ Foundation to help move this forward in a trial for pediatric brain tumor patients.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
CONCLUSIONS: - Anti-CD155 antibody D3G7H achieves monospecific detection of CD155 in immunoblots of tumor homogenates and immunohistochemistry of tumor FFPE sections. Our assay has utility in defining appropriate use of PVSRIPO in oncolytic immunotherapy against malignant glioma and other cancer histotypes. PMID: 28829151 [PubMed - as supplied by publisher]
Source: Archives of Pathology and Laboratory Medicine - Category: Laboratory Medicine Authors: Tags: Arch Pathol Lab Med Source Type: research
Treatment Terms Cancer Brain tumor Additional SEO Keywords brain tumor, glioblastoma, 60 minutes, brain cancer, poliovirus, polio virus SEO Meta Description CBS's 60 Minutes updates viewers on the polio virus therapy for brain tumor developed and tested at Duke's Preston Robert Tisch Brain Tumor Center. Author Sarah Avery Sub-Title FDA's breakthrough therapy designation expedites development Overview In a poignant, two-part segment May 15, 2016, CBS’s 60 Minutes returned to Duke to update viewers on the poliovirus therapy developed and t...
Source: dukehealth.org: Duke Health News - Category: Consumer Health News Authors: Source Type: news
To hear the words "cancer" and "cure" in the same sentence from experienced cancer researchers is both breathtaking and unexpected. Researchers and top oncologists are usually cautious to a fault. To hear that Congress is again trying to squeeze cancer research budgets is breathtaking but predictable. They've become frugal, also to a fault. Such is the cruel irony facing cancer patients and researchers today. Building on over 50 years of scientific progress, research leaders from cancer centers across the country are achieving stunning results that have led even the most guarded of them to use such ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
As we move towards the end of the year, like all news sources, we fall back on that classic space filler – the list story. So without further ado, here is the official Behind the Headlines Top Five of Top Fives stories of 2014, in which we celebrate the good, highlight the bad, check out the weird and answer some of the burning questions of the year. The top five 'Good work boffins!' stories of the year We can often get bogged down in pointing out dodgy sub-group analyses, spurious extrapolations of sample sizes containing just 20 rats and a water maze, and RCTs pointing out the benefits of cherries on dementia preve...
Source: NHS News Feed - Category: Consumer Health News Tags: QA articles Medical practice Source Type: news
More News: Brain | Brain Cancers | Brain Tumor | Cancer | Cancer & Oncology | Cancer Therapy | Genetics | Health | Neurology | Polio