Inverse treatment planning for spinal robotic radiosurgery: an international multi-institutional benchmark trial.

Inverse treatment planning for spinal robotic radiosurgery: an international multi-institutional benchmark trial.
J Appl Clin Med Phys. 2016;17(3):6151
Authors: Blanck O, Wang L, Baus W, Grimm J, Lacornerie T, Nilsson J, Luchkovskyi S, Palazon Cano I, Shou Z, Ayadi M, Treuer H, Viard R, Siebert FA, Chan MK, Hildebrandt G, Dunst J, Imhoff D, Wurster S, Wolff R, Romanelli P, Lartigau E, Semrau R, Soltys SG, Schweikard A
Abstract
Stereotactic radiosurgery (SRS) is the accurate, conformal delivery of high-dose radiation to well-defined targets while minimizing normal structure doses via steep dose gradients. While inverse treatment planning (ITP) with computerized optimization algorithms are routine, many aspects of the planning process remain user-dependent. We performed an international, multi-institutional benchmark trial to study planning variability and to analyze preferable ITP practice for spinal robotic radiosurgery. 10 SRS treatment plans were generated for a complex-shaped spinal metastasis with 21 Gy in 3 fractions and tight constraints for spinal cord (V14Gy < 2 cc, V18Gy < 0.1 cc) and target (coverage > 95%). The resulting plans were rated on a scale from 1 to 4 (excellent-poor) in five categories (constraint compliance, optimization goals, low-dose regions, ITP complexity, and clinical acceptability) by a blinded review panel. Additionally, the plans were mathemati-cally rated based on plan indices (cri...

Source: Journal of Applied Clinical Medical Physics - May 15, 2016 Category: Physics Authors: Blanck O, Wang L, Baus W, Grimm J, Lacornerie T, Nilsson J, Luchkovskyi S, Palazon Cano I, Shou Z, Ayadi M, Treuer H, Viard R, Siebert FA, Chan MK, Hildebrandt G, Dunst J, Imhoff D, Wurster S, Wolff R, Romanelli P, Lartigau E, Semrau R, Soltys SG, Schweik Tags: J Appl Clin Med Phys Source Type: research