Exogenous α-Synuclein Monomers Alter Dopamine Metabolism in Murine Brain.

In this study we investigated the influence of cerebral injection of human ASN on dopaminergic system activity. We have demonstrated that a single injection of ASN monomers into the substantia nigra pars compacta or striatum is sufficient to affect dopaminergic neurotransmission in murine nigro-striatal system.
PMID: 27161373 [PubMed - as supplied by publisher]

Source: Neurochemical Research - May 8, 2016 Category: Neuroscience Authors: Wawer A, Joniec-Maciejak I, Sznejder-Pachołek A, Schwenkgrub J, Ciesielska A, Mirowska-Guzel D Tags: Neurochem Res Source Type: research