Abstract PR04: Germline loss of PK-M2 promotes metabolic syndrome and hepatocellular carcinoma

This study will allow us to elucidate the distinct cell-intrinsic and cell-extrinsic roles of PK-M2 in both maintaining normal systemic metabolism and aberrant proliferation in the context of cancer.This abstract is also presented as Poster B25.Citation Format: Talya L. Dayton, Vasilena Gocheva, Kathryn M. Miller, William J. Israelsen, Clary B. Clish, Arjun Bhutkar, Shawn M. Davidson, Alba Luengo, Matthew G. Vander Heiden, Tyler E. Jacks. Germline loss of PK-M2 promotes metabolic syndrome and hepatocellular carcinoma. [abstract]. In: Proceedings of the AACR Special Conference: Developmental Biology and Cancer; Nov 30-Dec 3, 2015; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Res 2016;14(4_Suppl):Abstract nr PR04.

Source: Molecular Cancer Research - May 2, 2016 Category: Cancer & Oncology Authors: Dayton, T. L., Gocheva, V., Miller, K. M., Israelsen, W. J., Clish, C. B., Bhutkar, A., Davidson, S. M., Luengo, A., Heiden, M. G. V., Jacks, T. E. Tags: Other Topics: Oral Presentations - Proffered Abstracts Source Type: research