Research and Reviews in the Fastlane 133

This study certainly suggests a benefit to using Dexmedetomidine in these patients. Recommended by: Nudrat Rashid The Best of the Rest Emergency Medicine Beadle KL et al. Isopropyl alcohol nasal inhalation for nausea in the Emergency Department: A randomized controlled trial. Ann Emerg Med. 2015. PMID: 26679977 This is a small double-blinded RCT comparing inhaled isopropyl alcohol to saline placebo for short-term relief of nausea in the ED. Although it is hard to believe patients (and possibly investigators) were truly blinded to the odor of isopropanol, this study found isopropanol superior to placebo for improvement of nausea at ten minutes. This effect may be short lived however, as there was no difference in subsequent use of antiemetics between the two groups. In light of recent attention to possible side effects of existing medications, including prolongation of the QT interval with ondansetron, isopropyl alcohol pads offer an intriguing option for short-term relief of nausea in the ED. Recommended by: Meghan Spyres Emergency Medicine Chang AK, et al. Efficacy of an Acute Pain Titration Protocol Driven by Patient Response to a Simple Query: Do You Want More Pain Medication? Annals of Emerg Med. 2015. PMID: 26074387 How can you tell if your patient needs more pain medicine? This study supports the common sense approach: just ask them. I’ve always liked this approach, and it left 97% of patients satisfied or very satisfied with their pain control. T...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Education Emergency Medicine Intensive Care Neurology Neurosurgery critical care examination R&R in the FASTLANE recommendations research and reviews Resuscitation Source Type: blogs

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Background: Despite the critical role that Emergency Medical Services (EMS) provides in the health care system, racial/ethnic treatment disparities in EMS remain relatively unexamined. Objective: To investigate racial/ethnic treatment disparities in pain assessment and pain medication administration in EMS. Research Design: A retrospective analysis was performed on 25,732 EMS encounters from 2015 to 2017 recorded in the Oregon Emergency Medical Services Information System using multivariate logistic regression models to examine the role of patient race/ethnicity in pain assessment and pain medication administration...
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
Abstract Treatment of pilon fractures remains challenging due to the difficulty of fracture reduction and associated soft tissue complications. The aim of this study was to evaluate the pitfalls and strategies of posterior column reduction in the treatment of complex tibial pilon fractures (AO/OTA 43-C3). Thirteen AO/OTA classification 43-C3 type pilon fractures treated between January 2013 and January 2016 were retrospectively analyzed. Nine cases were treated by external fixation within 26 hours (range, 6-56 hours) after injury. The definitive open reduction and internal fixation (ORIF) was performed after the w...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
The objective of this study was to evaluate associations between marijuana use and the prevalence, severity, and rate of occurrence of tinnitus.Study designCross-sectional analysis of nationally representative data.SettingNational Health and Nutrition Examination Survey 2011–2012.Subjects and methodsStatistical analysis was performed on data collected from 2705 non-institutionalized adults aged 20–69 who underwent audiometric testing and were administered questionnaires about hearing, drug use, current health status, and medical history.ResultsThe use of marijuana at least once per month for the previous 12 m...
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Publication date: Available online 13 November 2019Source: Saudi Pharmaceutical JournalAuthor(s): María Esperanza Adrover, Marisa Pedernera, Magali Bonne, Bénédicte Lebeau, Verónica Bucalá, Loreana GalloAbstractAlbendazole (ABZ, anti-parasitic active pharmaceutical ingredient) is a crystalline low water-soluble drug, thus the dissolution rate in gastrointestinal fluids is limited. Consequently, the improvement of the water solubility and dissolution rate of ABZ implies a great challenge for a more efficient treatment of hydatidosis. In this context, SBA-15 and SBA-16 ordered mesoporous si...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
ConclusionThe ruthenium(II) complex showed beneficial effects as it ameliorated and prevented the progression of diabetes-related liver derangements while eliminating the hepatotoxicity associated with the use of metal compounds. However, further studies are still required to further determine the physiological mechanisms behind this effect.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research
ConclusionsCeramic firing affected the marginal gap; however, all Co-Cr frameworks had a marginal gap lower than 120 μm, which is reported to be a clinically acceptable limit. Most of the specimens (80%) had a metal-ceramic bond strength value higher than the 25-MPa ISO 9693 requirement. Five of 28 dental laboratory technicians were not able to comply with ceramic firing instructions.
Source: The Journal of Prosthetic Dentistry - Category: Dentistry Source Type: research
This study aimed to determine the effects of back massage on postoperative vital signs, pain, and comfort levels in liver transplant patients.MethodsA quasi-experimental model with a pretest, a posttest, and a control group was used. The population of the study comprised adult patients who had liver transplantation for the first time. The study sample comprised 84 adult patients who had liver transplantation: 42 experimental (study group) and 42 control group, selected by power analysis and the random sampling method from the population. The data were collected between May and September 2016 using the short-form McGill Pai...
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
We report the case of a 47-year-old man who was diagnosed with severe right ventricular outflow tract (RVOT) stenosis due to a space-occupying lesion; the diagnosis was made using computed tomography. He underwent mass reduction, pulmonary valve replacement, and RVOT reconstruction with a bovine pericardial patch. The pathological diagnosis was undifferentiated pleomorphic sarcoma originating from the myocardium. As the mass resection was incomplete, he received heavy particle therapy. He did not want to receive adjuvant chemotherapy. Four months later, severe RVOT stenosis recurred because the residual mass had invaded th...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Authors: Magno Pereira V, Marote Correia L, Rodrigues T, Serrão Faria G Abstract The posterior reversible encephalopathy syndrome is a neurological syndrome characterized by headache, confusion, visual disturbances and seizures associated with identifiable areas of cerebral edema on imaging studies. The authors report the case of a man, 33 years-old, leukodermic with a history of chronic alcohol and tobacco consumption, who is admitted to the emergency department for epigastric pain radiating to the back and vomiting with about six hours of evolution and an intense holocranial headache fo...
Source: Acta Medica Portuguesa - Category: Journals (General) Tags: Acta Med Port Source Type: research
Conclusions: Many unnecessary tests are obtained to evaluate syncope. Selecting tests based on history and examination and prioritizing less expensive and higher yield tests would ensure a more informed and cost-effective approach to evaluating older patients with syncope._____________________________________________________________________________4)    Reed MJ.  The ROSE (Risk Stratification of syncope in the emergency department) Study.  J Am Coll Cardiol, 2010; 55:713-721, doi:10.1016/j.jacc.2009.09.049  Objectives: The aim of this study was to develop and validate a clinical deci...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
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