Low birthweight linked to higher mortality right up to adolescence

Act against risk factors for low birthweight, to reduce numbers of vulnerable babiesRelated items from OnMedicaDaily iron supplement during pregnancy improves birthweightLow birthweight linked with infertility later in lifeCannabis use in pregnancy linked to low birthweight and intensive careBreastfeeding could cut children’s leukaemia riskFoetal alcohol syndrome must be better recognised
Source: OnMedica Latest News - Category: UK Health Source Type: news

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Authors: Mierzyński R, Dłuski DF, Gogacz M, Golubka I, Leszczyńska-Gorzelak B PMID: 30244628 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
This study sought to evaluate the associations between background exposures and psychological determinants, among postpartum Jewish and Arab women, relative to actual prenatal test endorsement. The independent and aggregative effects of contextual features and the subjective opinions and attitudes relative to a prenatal testing were evaluated, using logistic regressions. After accounting for contextual features, Jews with positive vs. negative opinions on screening were significantly more likely to undergo a prenatal screening. Specifically, having more favourable ideas on pregnancy termination, among Jews, was associated ...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
This study aims to investigate the relationship between ERCC5 polymorphism and the breast cancer risk in the lower northeastern region women of Thailand. One hundred fifty five samples from breast cancer patients and 122 samples from healthy control group were analysed. Genomic DNA was extracted from white blood cell of all samples. The real-time polymerase chain reaction (qPCR) was used to demonstrate genetic polymorphism of ERCC5. The results showed that the ERCC5 rs751402 polymorphism variant AG was associated with an increased risk of breast cancer. The frequency of ERCC5 rs751402 in patients with breast cancer was hig...
Source: International Journal of Molecular Epidemiology and Genetics - Category: Genetics & Stem Cells Tags: Int J Mol Epidemiol Genet Source Type: research
Conclusion Our study found that preterm PE significantly correlated with higher incidence of PEs, neonatal morbidities, also higher liver and kidney function compared to term PE. These results may be helpful for obstetricians to make accurate quantification of risk regarding every result of antenatal check-up, and perform close follow up if any abnormalities were found on blood pressure, ultrasound, or blood tests. PMID: 30246594 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Contributors : I Moelter ; J Schott ; D Lindner ; G Stoecklin ; K D öhner ; M Lübbert ; I E Gentle ; G HäckerSeries Type : Expression profiling by arrayOrganism : Mus musculusMutations in the transcription factor C/EBP α are found in about 10% of all acute myeloid leukaemia (AML) cases but the contribution of these mutations to leukaemogenesis is incompletely understood. We here use a mouse model of granulocyte progenitors expressing conditionally active HoxB8 to assess the cell biological and molecular activity of C/EBPα-mutations associated with human AML.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
Conclusion: In this study the prevalence of anemia in pregnancy was low compared to the findings of others. Gestational age (trimester) and iron/folic acid supplementation were statistically associated with anemia. Therefore, iron supplementation and health education to create awareness about the importance of early booking for antenatal care are recommended to reduce anemia. PMID: 30245724 [PubMed]
Source: Advances in Hematology - Category: Hematology Tags: Adv Hematol Source Type: research
Contributors : James F Padbury ; Jessica SchusterSeries Type : Methylation profiling by high throughput sequencingOrganism : Homo sapiensPreterm birth is a significant clinical problem and an enormous burden on society, affecting one in eight pregnant women and their newborns. Despite decades of research, its pathogenesis remains unclear. Many studies have shown that preterm birth is associated with health risks across the later life course. The “fetal origins” hypothesis postulates that adverse intrauterine exposures are associated with later disease susceptibility. Our recent studies have focused on the plac...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by high throughput sequencing Homo sapiens Source Type: research
Authors: Kapaya H, Williams R, Elton G, Anumba D Abstract Background: Despite major advances in perinatal medicine, intrapartum asphyxia remains a leading and potentially preventable cause of perinatal mortality and long-term morbidity. The umbilical cord pH is considered an essential criteria for the diagnosis of acute intrapartum hypoxic events. The purpose of this study was to evaluate whether obstetric risk factors are associated with fetal acidaemia at delivery. Methodology: In a case-control study, 294 women with term singleton pregnancies complicated by an umbilical artery cord pH 7.20. Groups were compa...
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
Authors: Martins MEP, Esmeraldo CUP, Sabiá JPD, Carvalho JHL, Suano-Souza FI, Sarni ROS Abstract Objective: To evaluate postpartum vitamin D deficiency/insufficiency and to relate it to pregestational BMI, gestational weight gain, and sociodemographic variables. Methods: This is a cross-sectional study with 225 full-term pregnant women. Data collected are as follows: maternal health, socioeconomic status, pregestational body mass index (BMI), and gestational weight gain. Laboratory evaluation included vitamin D [25(OH)D], calcium, phosphorus, magnesium, and alkaline phosphatase. Results: The mean age...
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
Authors: Chaikof M, Sobel M, Gandhi S PMID: 30244997 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
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