Correlation between the level of microRNA expression in peripheral blood mononuclear cells and symptomatology in patients with generalized anxiety disorder
This study investigated the correlation between the level of microRNA expression in peripheral blood mononuclear cells (PBMCs) and symptomatology in patients with generalized anxiety disorder (GAD). MicroRNA array was performed in peripheral blood mononuclear cells (PBMCs) obtained from GAD patients with gender, age, ethnicity-matched healthy controls. Then real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used to verify the top 7 miRNAs with the highest fold-change values in 76 GAD patients and 39 healthy controls.
Source: Comprehensive Psychiatry - Category: Psychiatry Authors: Sheng-dong Chen, Xin-yang Sun, Wei Niu, Ling-ming Kong, Ming-jun He, Hui-min Fan, Wan-shuai Li, Ai-fang Zhong, Li-yi Zhang, Jim Lu Source Type: research