Gastric tumour-derived ANGPT2 regulation by DARPP-32 promotes angiogenesis

Conclusions Our novel findings establish the role of DARPP-32-STAT3 axis in regulating ANGPT2 in cancer cells to promote angiogenesis and tumorigenesis.

http://gut.bmj.com/cgi/content/short/65/6/925?rss=1

Source: Gut - May 9, 2016 Category: Gastroenterology Authors: Chen, Z., Zhu, S., Hong, J., Soutto, M., Peng, D., Belkhiri, A., Xu, Z., El-Rifai, W. Tags: Pancreatic cancer Stomach Source Type: research