Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model

Gene-based virotherapy mediated by oncolytic viruses is currently experiencing a renaissance in cancer therapy. However, relatively little attention has been given to the potentiality of dual gene virotherapy ...

Source: Journal of Experimental and Clinical Cancer Research - May 6, 2016 Category: Cancer & Oncology Authors: Adel Galal El-Shemi, Ahmad Mohammed Ashshi, Youjin Na, Yan Li, Mohammed Basalamah, Faisal Ahmad Al-Allaf, Eonju Oh, Bo-Kyeong Jung and Chae-Ok YUN Source Type: research