Effects of Ginkgo biloba extract EGb 761® on cognitive control functions, mental activity of the prefrontal cortex and stress reactivity in elderly adults with subjective memory impairment – a randomized double‐blind placebo‐controlled trial

ConclusionWe observed indications for improved cognitive flexibility without changes in brain activation, suggesting increased processing efficiency with EGb761. Together with a trend for improved response inhibition results are compatible with mild enhancement of prefrontal dopamine. These conclusions on potential beneficial effect of EGb761 on prefrontal dopaminergic functions should be confirmed by direct measurements. © 2016 The Authors. Human Psychopharmacology: Clinical and Experimental published by John Wiley & Sons, Ltd.

Source: Human Psychopharmacology: Clinical and Experimental - May 4, 2016 Category: Psychiatry Authors: Stefanie M. Beck, Hannes Ruge, Christoph Schindler, Martin Burkart, Robert Miller, Clemens Kirschbaum, Thomas Goschke Tags: Research Article Source Type: research