Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer [Urologic Oncology]

Conclusion
Specific sites of metastases in men with mCRPC are associated with differential OS, with successive increased lethality for lung and liver metastases compared with bone and nonvisceral involvement. These data may help in treatment decisions, the design of future clinical trials, and understanding the variation in biology of different sites of metastases in men with mCRPC.

Source: Journal of Clinical Oncology - May 2, 2016 Category: Cancer & Oncology Authors: Halabi, Kelly, Ma, Zhou, Solomon, Fizazi, Tangen, Rosenthal, Petrylak, Hussain, Vogelzang, Thompson, Chi, de Bono, Armstrong, Eisenberger, Fandi, Li, Araujo, Logothetis, Quinn, Morris, Higano, Tannock, Small Tags: Prognostic Studies Urologic Oncology Source Type: research