Dosimetric advantages of intensity-modulated proton therapy for oropharyngeal cancer compared with intensity-modulated radiation: A case-matched control analysis

A potential advantage of intensity-modulated proton therapy (IMPT) over intensity-modulated (photon) radiation therapy (IMRT) in the treatment of oropharyngeal carcinoma (OPC) is lower radiation dose to several critical structures involved in the development of nausea and vomiting, mucositis, and dysphagia. The purpose of this study was to quantify doses to critical structures for patients with OPC treated with IMPT and compare those with doses on IMRT plans generated for the same patients and with a matched cohort of patients actually treated with IMRT.

Source: Medical Dosimetry - May 2, 2016 Category: Radiology Authors: Emma B. Holliday, Esengul Kocak-Uzel, Lei Feng, Nikhil G. Thaker, Pierre Blanchard, David I. Rosenthal, G. Brandon Gunn, Adam S. Garden, Steven J. Frank Source Type: research