Isotretinoin therapy for the treatment of acne in patients with cystic fibrosis: a case series and review of the literature.

We describe two patients with CF treated with isotretinoin from our clinic and also provide a literature review of 11 similar cases. We describe patient outcomes, common complications, and the risks for severe adverse effects. MATERIALS AND METHODS: The clinical courses of two patients with CF who were treated with isotretinoin for moderate-severe acne are presented. Using PubMed, we analyzed previous case reports of patients with CF who were prescribed isotretinoin and review complications associated with systemic retinoids. RESULTS: Based on a synthesis of the literature and our own experience, it appears that isotretinoin therapy for CF patients with moderate-severe acne may be an appropriate option when clinically indi ated. If dermatologists monitor lab values and adverseeffects carefully, patients with CF can benefit from isotretinoin therapy. PMID: 27136632 [PubMed - as supplied by publisher]
Source: Dermatol Online J - Category: Dermatology Authors: Tags: Dermatol Online J Source Type: research