CardioBrief: Rosuvastatin Goes Generic, Major Role Expected

(MedPage Today) -- Finally there's a challenger to the long reign of atorvastatin, experts say
Source: MedPage Today Public Health - Category: American Health Source Type: news

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Publication date: Available online 18 May 2019Source: PeptidesAuthor(s): Allison B. Reiss, Daniel S. Glass, Eric Lam, Amy D. Glass, Joshua De Leon, Lora J. KasselmanAbstractCardiovascular disease (CVD) remains the leading cause of death worldwide, despite multiple treatment options. In addition to elevated lipid levels, oxidative stress and inflammation are key factors driving atherogenesis and CVD. New strategies are required to mitigate risk and most urgently for statin-intolerant patients. The neuropeptide hormone oxytocin, synthesized in the brain hypothalamus, is worthy of consideration as a CVD ancillary treatment be...
Source: Peptides - Category: Biochemistry Source Type: research
Authors: Strilchuck L, Fogacci F, Cicero AF Abstract INTRODUCTION: Cardiovascular (CV) diseases are the leading cause of death and disability in the developed countries. Lipid-lowering therapy is a cornerstone of the CV risk modification strategy. The first line treatment for hyperlipidemia is statins, which decrease low-density lipoprotein cholesterol (LDL-C) by 30-50% and proportionally reduce the CV events. However, they are not always enough to achieve LDL-C goals in many patients, and some patients are statin intolerant. For this reason, new powerful injectable lipid-lowering drugs have been developed. Areas c...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
Authors: Liu J, Wang K, Liu H, Zhao H, Zhao X, Lan Y, Huang W, Wang H Abstract Increasing of arterial stiffness is the pathophysiological characteristic of hypertension. Carotid-femoral pulse wave velocity (CF-PWV) is an index of arterial stiffness. Serum uric acid has been found to be involved the development of hypertension. We investigated the relationship between CF-PWV and serum uric acid in subjects with hypertension and hyperuricemia. 651 subjects (M/F 271/380) were divided into four groups, group 1: subjects without hypertension and hyperuricemia; group 2: hypertension subjects without hyperuricemia; group ...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
It is important to understand patients' experiences of statin-associated adverse effects to potentially identify those at risk for stopping treatment.
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Tags: Original Research Source Type: research
Authors: Quezada-Fernández P, Trujillo-Quiros J, Pascoe-González S, Trujillo-Rangel WA, Cardona-Müller D, Ramos-Becerra CG, Barocio-Pantoja M, Rodríguez-de la Cerda M, Nérida Sánchez-Rodríguez E, Cardona-Muñóz EG, García-Benavides L, Grover-Páez F Abstract Type 2 diabetes mellitus (T2DM) is associated with premature atherosclerosis and arterial stiffening due to the accumulation of advanced glycation end-products in vessel walls. Green tea polyphenols are considered cardio-protective substances. In this randomised double-blind placebo-contro...
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
ConclusionAspirin use may have chemo-preventive effect on recurrence of hepatitis B virus-related HCC after curative resection.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
For the 16 years that Dr. Brian Westerberg, a Canadian surgeon, worked volunteer missions at the Mulago National Referral Hospital in Kampala, Uganda, scarcity was the norm. The patients usually exceeded the 1,500 allotted beds. Running water was once cut off when the debt-ridden hospital was unable to pay its bills. On some of his early trips, Westerberg even brought over drugs from Canada in order to treat patients. But as low-cost generics made in India and China became widely available through Uganda’s government and international aid agencies in the early 2000s, it seemed at first like the supply issue had been ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized generic drugs medication medicine Source Type: news
Title: Lipitor (atorvastatin) vs. Vytorin (simvastatin and ezetimibe)Category: MedicationsCreated: 5/17/2019 12:00:00 AMLast Editorial Review: 5/17/2019 12:00:00 AM
Source: MedicineNet Cholesterol General - Category: Cardiology Source Type: news
Title: Lipitor (atorvastatin) vs. Zetia (ezetimibe)Category: MedicationsCreated: 5/17/2019 12:00:00 AMLast Editorial Review: 5/17/2019 12:00:00 AM
Source: MedicineNet Cholesterol General - Category: Cardiology Source Type: news
Title: Lipitor (atorvastatin) vs. Niacin (nicotinic acid, vitamin B3)Category: MedicationsCreated: 5/17/2019 12:00:00 AMLast Editorial Review: 5/17/2019 12:00:00 AM
Source: MedicineNet Heart General - Category: Cardiology Source Type: news
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