Autism Spectrum Disorder and Complementary Health Approaches

Parents whose children have autism spectrum disorder may choose complementary health approaches for their affected children. Melatonin may help with ASD-associated sleep disorders and music therapy may have other positive effects, but the efficacy of other complementary health approaches is uncertain.
Source: NCCAM Featured Content - Category: Complementary Medicine Authors: Source Type: news

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Conclusions This study advances our understanding of sleep in ASD by showing that GID, NVIQ, sex, and age increased the odds of sleep problems in children with ASD. These results reinforce that healthcare professionals should screen for sleep problems in children with ASD and suggest future lines of inquiry.
Source: Research in Autism Spectrum Disorders - Category: Psychiatry Source Type: research
(University of Pennsylvania School of Medicine) Shinjae Chung, Ph.D. has been named a recipient of a 2017 Hartwell Individual Biomedical Research Award, to study the molecular basis of remedying sleep disturbances in autism spectrum disorder.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Publication date: Available online 22 May 2018 Source:Neuroscience Author(s): Christine E. Boone, Heydar Davoudi, Jon B. Harrold, David J. Foster Fragile X syndrome (FXS) is the most common heritable cause of intellectual disability and single-gene cause of autism spectrum disorder. The Fmr1 null mouse models much of the human disease including hyperarousal, sensory hypersensitivity, seizure activity, and hippocampus-dependent cognitive impairment. Sleep architecture is disorganized in FXS patients, but has not been examined in Fmr1 knockout (Fmr1-KO) mice. Hippocampal neural activity during sleep, which is implicated in ...
Source: Neuroscience - Category: Neuroscience Source Type: research
Abstract De novo variants of ASH1L, which encodes a histone methyltransferase, have been reported in a few patients with intellectual disability and autistic features. Here, we identified a novel de novo frame-shift variant, c.2422_2423delAAinsT which predicts p.(Lys808TyrfsTer40), in ASH1L in a patient with multiple congenital anomalies (MCA), fine motor developmental delay, learning difficulties, attention deficit hyperactivity disorder, sleep apnea, and scoliosis. This frame-shift variant is expected to result in loss-of-function. Our report provides further evidence to support loss-of-function alterations of A...
Source: European Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Eur J Med Genet Source Type: research
CONCLUSIONS: This study suggests that amantadine may be effective in the treatment of ESES-associated syndromes but warrants replication in a more rigorous study. PMID: 29754107 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
ConclusionsWe demonstrate two quantitative readouts of dysregulated sleep composition in children with AS —gamma coherence and spindles—and describe how functional connectivity patterns may be disrupted during wakefulness. Quantitative EEG phenotypes have potential as biomarkers and readouts of target engagement for future clinical trials and provide clues into how neural circuits are dysregulated i n children with AS.
Source: Molecular Autism - Category: Molecular Biology Source Type: research
Publication date: 18 April 2018 Source:Neuron, Volume 98, Issue 2 Author(s): Alexandra Krol, Ralf D. Wimmer, Michael M. Halassa, Guoping Feng Diagnoses of behavioral disorders such as autism spectrum disorder and schizophrenia are based on symptomatic descriptions that have been difficult to connect to mechanism. Although psychiatric genetics provide insight into the genetic underpinning of such disorders, with a majority of cases explained by polygenic factors, it remains difficult to design rational treatments. In this review, we highlight the value of understanding neural circuit function both as an intermediate level ...
Source: Neuron - Category: Neuroscience Source Type: research
Happy Saturday, sweet readers! Did everyone survive yesterday? Or did you even realize it was Friday 13th? Honestly, I didn’t remember until around noon yesterday. To quote the great Michael Scott, “I’m not superstitious, but I am a little stitious.” In other words, I didn’t wake up and begin anxiously awaiting doom around every corner, but, once I did remember what day it was…I kept an eye open. It’s only human nature. Anyway, let’s get on with everything this week’s Psychology Around the Net has to offer which includes science-backed ways to boost creativity, how to ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Alzheimer's Bipolar Celebrities Children and Teens College Creativity Disorders Happiness Phobia Psychology Around the Net Research Sleep Women's Issues Alzheimer's disease Bipolar Disorder brain Creative Thinking Embarra Source Type: blogs
Genetic studies point to the thalamic reticular nucleus (TRN) in the pathogenesis of ASD. The TRN modulates sensory processing and attention by gating thalamocortical communication during wake, and propagates spindles during sleep (oscillations critical for memory consolidation). Here, we investigated whether thalamocortical functional connectivity is abnormal in ASD. Because motion artifacts may create spurious group differences, we used pre-scan training and strict data quality inclusion criteria to prevent and control for motion confounds.
Source: Biological Psychiatry - Category: Psychiatry Authors: Source Type: research
We present the case of a 12-year-old child with atypical autism who developed psychotic symptoms that led to a diagnostic dilemma. Proper exploration of early childhood history, prompt treatment with an antipsychotic medication, and social skill training led to resolution of psychotic symptoms and improvement in disruptive symptoms of autism. Keywords: Autism, psychosis, association, autism spectrum disorder, ASD Since the concept of psychosis by Blueler 1 and Kraeplin2 first emerged, autism spectrum disorder (ASD) was thought to be an early manifestation of psychosis or schizophrenia, and ASD in children was referred as &...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue ASD association autism autism spectrum disorder psychosis Source Type: research
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