Risk factors for malignancy in systemic sclerosis patients.

Risk factors for malignancy in systemic sclerosis patients. Clin Rheumatol. 2016 Apr 27; Authors: Kaşifoğlu T, Yaşar Bilge Ş, Yıldız F, Özen G, Pehlivan Y, Yılmaz N, Tarhan F, Yılmaz S, Küçük A, Emmungil H, Koca SS, Çınar M, Direskeneli H, Erken E, Can G, Özmen M, Gönüllü E, Kisacik B, Aksu K, Karadağ O, Kasifoglu N, Arslantas D, Sahin F, Keser G, Yavuz S, Birlik M, Onat AM Abstract Systemic sclerosis (SSc) is an autoimmune connective tissue disease with multisystem involvement. An increased incidence of cancer in SSc patients compared with the general population has been reported in several reports. Our aims in this study were to determine the most common malignancies and to investigate the possible risk factors for the development of malignancy in patients with SSc. Three hundred forty SSc patients from 13 centers were included to the study. Data of the patients were obtained by evaluating their medical records retrospectively. A total of 340 patients with SSc were evaluated. Twenty-five of the patients had 19 different types of malignancy. Bladder cancer was the most common type of cancer with four patients and was followed by breast cancer with three patients, and cervix cancer and ovarian cancer with two patients each. Other types of cancers such as squamous cell skin cancer, adenocancer with an unknown origin, multiple myeloma, chronic myeloid leukemia, papillary thyroid cancer, larynx canc...
Source: Clinical Lymphoma and Myeloma - Category: Cancer & Oncology Authors: Tags: Clin Rheumatol Source Type: research

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