Evaluation of patients and families with concern for predispositions to hematologic malignancies within the Hereditary Hematologic Malignancy Clinic (HHMC)
The clinical importance and anticipated results of genetic counseling and testing for hereditary cancer syndromes in patients with hematologic malignancies is poorly defined. We evaluated 67 patients referred to the Hereditary Hematologic Malignancy Clinic at a single institution. A cancer predisposition syndrome was confirmed in twelve patients (18%). Identification of germline predispositions to malignancy provides insight for individualized treatment, and screening/surveillance opportunities for family members.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Courtney D. DiNardo, Sarah A. Bannon, Mark Routbort, Anna Franklin, Maureen Mork, Mary Armanios, Emily M. Mace, Jordan S. Orange, Meselle Jeff-Eke, Jane E. Churpek, Koichi Takahashi, Jeffrey L. Jorgensen, Guillermo Garcia-Manero, Steve Kornblau, Alison Be Tags: Original Study Source Type: research
More News: Cancer | Cancer & Oncology | Genetics | Hematology | Leukemia | Lymphoma | Middle East Health | Myeloma | Study