12 Mind-Blowing Stats Everyone Should Know About Infertility

Getting pregnant, if at all possible, is a lot harder than most people think. While about 60 percent of couples will conceive without medical assistance within six months of trying, one in eight couples are struggling with infertility issues. Infertility is commonly defined as the inability to get pregnant, or maintain a pregnancy, after adequately trying for 12 months (and in some cases for a full six months) without medical assistance. And while there is still so much we don’t really know about the condition, we do know that age, physical health and lifestyle choices can contribute to a person’s fertility, and we know that infertility affects men and women equally. A couple’s infertility is highly nuanced to the combination of both partners’ bodies, hormones and health issues, but the general fact of the matter is that infertility is a highly overlooked issue unless you are personally dealing with it. In honor of National Infertility Awareness Week, here are 12 statistics that will open your eyes to the condition. 7.4 Million The number of women between 15-44 in the United States who have difficulty getting and staying pregnant. That's 12 percent of all women, according to the U.S. Centers for Disease Control and Prevention. 7.5 The estimated percentage of sexually experienced men who have reported seeing a fertility doctor at least once, the CDC reports.  40 The percentage of struggling couples in which the male partner contributes to...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Introduction: Recurrent pregnancy loss represents a major health problem and is  one of the most common causes of female infertility. The association between thrombophilia and recurrent pregnancy loss (RPL) has become an undoubted fact
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 22 – Early Pregnancy, intrauterine insemination and PCOS Source Type: research
AbstractStudy objectiveTo compare pregnancy outcomes in PCOS women undergoing transvaginal ovarian injury (TVOI) and laparoscopic ovarian drilling (LOD)Design126 infertile patients with PCOS were included in this prospective cohort studyCanadian task force classification of level of evidenceIIA.SettingUniversity-affiliated fertility center.PatientsSixty-seven infertile patients with the history of failed in vitro maturation underwent follow-up as the TVOI group. Fifty-nine infertile women who underwent LOD acted as controls. All subjects had PCOS with menstrual irregularity and were anovulatory by repetitive serum progeste...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionNMR-based metabolic profiling may be successfully applied to find diagnostic biomarkers for PCOS and endometriosis and it might be also used to predict oocyte developmental potential and subsequent outcome.
Source: Metabolomics - Category: Biology Source Type: research
CONCLUSION: In addition to pharmacological interventions, long-term standardized individualized management of PCOS patients is needed to achieve fertility and reduce the risk of metabolic related diseases. PMID: 30706800 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with poor reproductive outcomes, including infertility and pregnancy complications, and poor metabolic outcomes, including insulin resistance, type 2 diabetes, and the metabolic syndrome. Prevalence estimates for PCOS range from 7% to 15% of reproductive-age women worldwide, depending on the diagnostic criteria used. Accordingly, PCOS-associated dysglycemia and obesity are a global public health risk. Despite the public health importance of PCOS, notable gaps exist in the literature regarding its pathophysiology, natural history, and optimal management.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
This study was planned to test whether follicular fluid (FF) levels of patatin-like phospholipase domain containing 3-gene (PNPLA3:adiponutrin), preptin, kisspeptin, and amylin change in polycystic ovarian syndrome (PCOS). A total of 40 infertile volunteers undergoing IVF/ICSI were included in the study. They were divided into two groups as PCOS (n=20) and control group without PCOS (n=20). The controls were recruited from subjects with a poor ovarian response. The PCOS and control participants were matched according to their body mass index (BMI). Each group of participants underwent ovarian stimulation with GnRH antagoni...
Source: Cellular and Molecular Biology - Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research
Abstract A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse reproductive outcomes in the perinatal/neonatal periods, childhood, adolescence, and even adulthood. The potential impact of Bisphenol A (BPA), Phthalates and Perfluoroalkyl substances (PFAS) on female reproduction, in particular on puberty, PCOS pathogenesis, infertility, ovarian function, endometriosis, and recurrent pregnancy loss, in both humans and animals, will be discussed in...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Conclusions: Primary disease characteristics of PCOS, chiefly hyperandrogenism and impaired glucose tolerance, predict suboptimal obstetric and neonatal outcomes. Increased surveillance during pregnancy should focus on women with PCOS and these features to help mitigate disease risk. PMID: 30590587 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Conclusion: Current research, although limited, suggests that genetics and epigenetics of infertility diagnosis affects disease and overall outcomes. In addition, other fertility treatments that also lead to adverse outcomes are aiding in the identification of factors, including the supraphysiologic hormonal environment that may impact overall success and healthy outcomes for mother and child. Further studies including genome wide associations studies, epigenomics studies as well as experimental studies are needed, to better identify factors leading to outcomes. PMID: 30561694 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Publication date: Available online 14 December 2018Source: Reproductive BioMedicine OnlineAuthor(s): Nasim Tabibnejad, Mohammad Hasan Sheikhha, Nasrin Ghasemi, Fesahat, Mehrdad Soleimani, Abbas AflatoonianAbstractResearch questionCan a combination of time-lapse morphokinetic parameters and cumulus cell gene expression in polycystic ovary syndrome (PCOS) women be used to predict assisted reproductive treatment outcome?DesignA total of 547 embryos from 100 intracytoplasmic sperm injection (ICSI) cycles were evaluated. Fifty women with PCOS and 50 women who were categorized as tubal factor infertility were recruited. Time-lap...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
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