Efficacy, Tolerability, and Safety of Cannabinoid Treatments in the Rheumatic Diseases: A Systematic Review of Randomized Controlled Trials

ConclusionExtremely small sample sizes, short study duration, heterogeneity of rheumatic conditions and products, and absence of studies of herbal cannabis allow for only limited conclusions for the effects of cannabinoids in rheumatic conditions. Pain relief and effect on sleep may have some potential therapeutic benefit, but with considerable mild to moderate adverse events. There is currently insufficient evidence to recommend cannabinoid treatments for management of rheumatic diseases pending further study.

Source: Arthritis Care and Research - April 26, 2016 Category: Rheumatology Authors: Mary‐Ann Fitzcharles, Peter A. Ste‐Marie, Winfried Häuser, Daniel J. Clauw, Shahin Jamal, Jacob Karsh, Tara Landry, Sharon Leclercq, Jason J. Mcdougall, Yoram Shir, Kam Shojania, Zach Walsh Tags: Rheumatic Diseases Source Type: research